Eight children, 8-15 years old, underwent patch aortoplasty across the supravalvular constriction between 1961 and 1974. The clinical course and hemodynamic alterations of these patients over the ensuing years is described. Changes in progression of left ventricular outflow tract obstruction, in aortic morphology and in valvular function occurred with the growth of these children. These new findings dictate strict, life-time follow up in patients undergoing patch aortoplasty for diffuse supravalvular aortic stenosis in childhood.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Intramural Research (Z01)
Project #
1Z01HL002770-01
Application #
3966651
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1986
Total Cost
Indirect Cost
Name
U.S. National Heart Lung and Blood Inst
Department
Type
DUNS #
City
State
Country
United States
Zip Code