The effects of glucose, sucrose (1.75gm/kg), aspartame (30mg/kg) and saccharin were compared for 32 preschool aged males: 19 had histories of adverse behavioral response to sugar while 13 were familiar playmates with no such histories. There was no evidence of behavioral response to sugar on measures of activity, aggression, expression emotionality or anxiety. There was a slight but significant decrease in actometer rated motor activity following aspartame ingestion, the significance of which is unclear. The response of children with generalized anxiety disorder and normal controls to caffeine (10 mg/kg) are being compared. To date, a total of four pairs have been examined with no evidence for greater responsivity of anxiety disordered children that controls. This is in contrast to studies with adult patients indicating caffeine hypersensitivity.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Intramural Research (Z01)
Project #
1Z01MH000161-07
Application #
4696308
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
7
Fiscal Year
1985
Total Cost
Indirect Cost
Name
U.S. National Institute of Mental Health
Department
Type
DUNS #
City
State
Country
United States
Zip Code