Our studies on global cerebral ischemia associated with cardiac arrest revealed striking neuronal changes in GABAergic neurons, as early as 15 minutes after recirculation. Although these changes may be of transitory nature, they may significantly influence the further development of ischemic injury. Further studies will be focussed on attempts to modify ischemic injury in global ischemia by pharmacological means related to GABAergic system.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Intramural Research (Z01)
Project #
1Z01NS002833-01
Application #
3860918
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1991
Total Cost
Indirect Cost
City
State
Country
United States
Zip Code