Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Intramural Research (Z01)
Project #
1Z01SC003800-27
Application #
6163255
Study Section
Surgery (SURG)
Project Start
Project End
Budget Start
Budget End
Support Year
27
Fiscal Year
1997
Total Cost
Indirect Cost
Name
National Cancer Institute Division of Clinical Sciences
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Wargo, Jennifer A; Robbins, Paul F; Li, Yong et al. (2009) Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression. Cancer Immunol Immunother 58:383-94
Robbins, Paul F; Li, Yong F; El-Gamil, Mona et al. (2008) Single and dual amino acid substitutions in TCR CDRs can enhance antigen-specific T cell functions. J Immunol 180:6116-31
Heemskerk, Bianca; Liu, Ke; Dudley, Mark E et al. (2008) Adoptive cell therapy for patients with melanoma, using tumor-infiltrating lymphocytes genetically engineered to secrete interleukin-2. Hum Gene Ther 19:496-510
Breunis, Willemijn B; Tarazona-Santos, Eduardo; Chen, Renee et al. (2008) Influence of cytotoxic T lymphocyte-associated antigen 4 (CTLA4) common polymorphisms on outcome in treatment of melanoma patients with CTLA-4 blockade. J Immunother 31:586-90
Palmer, Douglas C; Chan, Chi-Chao; Gattinoni, Luca et al. (2008) Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity. Proc Natl Acad Sci U S A 105:8061-6
Powell Jr, Daniel J; Attia, Peter; Ghetie, Victor et al. (2008) Partial reduction of human FOXP3+ CD4 T cells in vivo after CD25-directed recombinant immunotoxin administration. J Immunother 31:189-98
Klapper, Jacob A; Downey, Stephanie G; Smith, Franz O et al. (2008) High-dose interleukin-2 for the treatment of metastatic renal cell carcinoma : a retrospective analysis of response and survival in patients treated in the surgery branch at the National Cancer Institute between 1986 and 2006. Cancer 113:293-301
Yang, S; Cohen, C J; Peng, P D et al. (2008) Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition. Gene Ther 15:1411-23
Rosenberg, Steven A (2008) Why perform sentinel-lymph-node biopsy in patients with melanoma? Nat Clin Pract Oncol 5:1
Hinrichs, Christian S; Spolski, Rosanne; Paulos, Chrystal M et al. (2008) IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy. Blood 111:5326-33

Showing the most recent 10 out of 60 publications