Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Intramural Research (Z01)
Project #
1Z01SC004024-10
Application #
6163261
Study Section
Metabolism Study Section (MET)
Project Start
Project End
Budget Start
Budget End
Support Year
10
Fiscal Year
1997
Total Cost
Indirect Cost
Name
National Cancer Institute Division of Clinical Sciences
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Davis, R Eric; Zhang, Ya-Qin; Southall, Noel et al. (2007) A cell-based assay for IkappaBalpha stabilization using a two-color dual luciferase-based sensor. Assay Drug Dev Technol 5:85-103
Wiestner, Adrian; Tehrani, Mahsa; Chiorazzi, Michael et al. (2007) Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival. Blood 109:4599-606
Salaverria, Itziar; Zettl, Andreas; Bea, Silvia et al. (2007) Specific secondary genetic alterations in mantle cell lymphoma provide prognostic information independent of the gene expression-based proliferation signature. J Clin Oncol 25:1216-22
Iqbal, J; Greiner, T C; Patel, K et al. (2007) Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma. Leukemia 21:2332-43
Lenz, Georg; Nagel, Inga; Siebert, Reiner et al. (2007) Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma. J Exp Med 204:633-43
Annunziata, Christina M; Davis, R Eric; Demchenko, Yulia et al. (2007) Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell 12:115-30
Davies, Andrew J; Rosenwald, Andreas; Wright, George et al. (2007) Transformation of follicular lymphoma to diffuse large B-cell lymphoma proceeds by distinct oncogenic mechanisms. Br J Haematol 136:286-93
Kuo, Tracy C; Shaffer, Arthur L; Haddad Jr, Joseph et al. (2007) Repression of BCL-6 is required for the formation of human memory B cells in vitro. J Exp Med 204:819-30
Iqbal, Javeed; Neppalli, Vishala T; Wright, George et al. (2006) BCL2 expression is a prognostic marker for the activated B-cell-like type of diffuse large B-cell lymphoma. J Clin Oncol 24:961-8
Ngo, Vu N; Davis, R Eric; Lamy, Laurence et al. (2006) A loss-of-function RNA interference screen for molecular targets in cancer. Nature 441:106-10

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