Abstract

The Section is the statistical and data management component of the Center for Cancer Research (CCR). The Section provides statistical leadership and data management consultation for major activities of the Center, and is involved in the design, conduct, monitoring, and statistical analyses of intramural and national multicenter clinical trials of experimental treatments for cancer, and intramural clinical trials for treatment of AIDS. The section provides a broad range of data analysis and consultation services to laboratories performing basic scientific research into the origin and growth mechanisms of cancer and AIDS. Other major collaborative efforts include studies to identify important prognostic and treatment selection factors, evaluate diagnostic procedures, develop improved staging systems, and assist investigators in the design, execution, and analyses of major in vitro drug testing studies. The Section develops and implements new statistical designs and biometric methods related to the development and evaluation of new cancer and AIDS treatments. The Section maintains a unified system for tracking basic information on all patients registered on CCR treatment protocols. Approximately 20% of the Section's activities are HIV-AIDS related.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Division of Clinical Sciences - NCI (NCI)
Type
Intramural Research (Z01)
Project #
1Z01SC007202-22
Application #
7331251
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
22
Fiscal Year
2006
Total Cost
Indirect Cost

  Institution

Name
Clinical Sciences
Department
Type
DUNS #
City
State
Country
United States
Zip Code

  Publications

Gulley, James L; Arlen, Philip M; Tsang, Kwong-Yok et al. (2008) Pilot study of vaccination with recombinant CEA-MUC-1-TRICOM poxviral-based vaccines in patients with metastatic carcinoma. Clin Cancer Res 14:3060-9
Vaccari, Monica; Mattapallil, Joseph; Song, Kaimei et al. (2008) Reduced protection from simian immunodeficiency virus SIVmac251 infection afforded by memory CD8+ T cells induced by vaccination during CD4+ T-cell deficiency. J Virol 82:9629-38
Denduluri, Neelima; Yang, Sherry X; Berman, Arlene W et al. (2008) Circulating biomarkers of bevacizumab activity in patients with breast cancer. Cancer Biol Ther 7:15-20
Azad, Nilofer S; Posadas, Edwin M; Kwitkowski, Virginia E et al. (2008) Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity. J Clin Oncol 26:3709-14
Hadley, Donald W; Jenkins, Jean F; Steinberg, Seth M et al. (2008) Perceptions of cancer risks and predictors of colon and endometrial cancer screening in women undergoing genetic testing for Lynch syndrome. J Clin Oncol 26:948-54
Hoffman, Karen E; Derdak, Joanne; Bernstein, Donna et al. (2008) Metabolic syndrome traits in long-term survivors of pediatric sarcoma. Pediatr Blood Cancer 50:341-6
Toubaji, Antoun; Achtar, Moujahed; Provenzano, Maurizio et al. (2008) Pilot study of mutant ras peptide-based vaccine as an adjuvant treatment in pancreatic and colorectal cancers. Cancer Immunol Immunother 57:1413-20
Miao, Ning; Pingpank, James F; Alexander, H Richard et al. (2008) Percutaneous hepatic perfusion in patients with metastatic liver cancer: anesthetic, hemodynamic, and metabolic considerations. Ann Surg Oncol 15:815-23
Hamada, Akinobu; Sissung, Tristan; Price, Douglas K et al. (2008) Effect of SLCO1B3 haplotype on testosterone transport and clinical outcome in caucasian patients with androgen-independent prostatic cancer. Clin Cancer Res 14:3312-8
Sissung, Tristan M; Danesi, Romano; Price, Douglas K et al. (2008) Association of the CYP1B1*3 allele with survival in patients with prostate cancer receiving docetaxel. Mol Cancer Ther 7:19-26

Showing the most recent 10 out of 127 publications