Emerging/re-emerging zoonotic diseases are a major global health problem. Linking comprehensive pathogen surveillance of arthropod/vector populations in Uganda with public health surveillance at the regional and international level will make an important contribution to human and animal health in East Africa and the One World One Health concept in general. There will be a focus on rodent-borne pathogens potentially causing disease in humans, wildlife and livestock. A more comprehensive understanding of the ecology of known and unknown rodent-borne zoonotic pathogens is essential for a risk assessment for local and global human and animal health. The establishment of an emerging/re-emerging virus program in Rakai, Uganda is ongoing. The necessary equipment to start investigations into emerging viral disease in the region have been procured and will be transported to Uganda in the following fiscal year. The current Ebola virus outbreak in West Africa has resulted in a planned field expedition to set up the lab and initiate rodent and insect trapping as well as establishing contacts with the regional health authorities to be delayed until the next fiscal year.
| Hawman, David W; Haddock, Elaine; Meade-White, Kimberly et al. (2018) Favipiravir (T-705) but not ribavirin is effective against two distinct strains of Crimean-Congo hemorrhagic fever virus in mice. Antiviral Res 157:18-26 |
| Zivcec, Marko; Safronetz, David; Scott, Dana P et al. (2018) Nucleocapsid protein-based vaccine provides protection in mice against lethal Crimean-Congo hemorrhagic fever virus challenge. PLoS Negl Trop Dis 12:e0006628 |
| Strong, James E; Feldmann, Heinz (2017) The Crux of Ebola Diagnostics. J Infect Dis 216:1340-1342 |
| Prescott, Joseph B; Marzi, Andrea; Safronetz, David et al. (2017) Immunobiology of Ebola and Lassa virus infections. Nat Rev Immunol 17:195-207 |
| Baseler, Laura; Chertow, Daniel S; Johnson, Karl M et al. (2017) The Pathogenesis of Ebola Virus Disease. Annu Rev Pathol 12:387-418 |
| Yoshida, Reiko; Muramatsu, Shino; Akita, Hiroshi et al. (2016) Development of an Immunochromatography Assay (QuickNavi-Ebola) to Detect Multiple Species of Ebolaviruses. J Infect Dis : |
| Haddock, Elaine; Feldmann, Friederike; Feldmann, Heinz (2016) Effective Chemical Inactivation of Ebola Virus. Emerg Infect Dis 22:1292-4 |
| Hoenen, Thomas; Groseth, Allison; Rosenke, Kyle et al. (2016) Nanopore Sequencing as a Rapidly Deployable Ebola Outbreak Tool. Emerg Infect Dis 22:331-4 |
| Sprecher, Armand G; Caluwaerts, An; Draper, Mike et al. (2015) Personal Protective Equipment for Filovirus Epidemics: A Call for Better Evidence. J Infect Dis : |
| Ogawa, Hirohito; Miyamoto, Hiroko; Nakayama, Eri et al. (2015) Seroepidemiological Prevalence of Multiple Species of Filoviruses in Fruit Bats (Eidolon helvum) Migrating in Africa. J Infect Dis : |
Showing the most recent 10 out of 11 publications
