The NIH Center for Regenerative Medicine (NIH CRM) represents a new initiative within the intramural program, which is supported by the Common Fund. On August 1, 2011, Mahendra Rao was hired as the first Director of the NIH CRM. His efforts will be shared between the Center and his own lab. Since arriving on campus, Dr. Rao has been orchestrating the renovation and establishment of his lab. We are currently in the process of recruiting laboratory staff (post docs and staff scientists) and purchasing the required tools and reagents to perform our research. There has also been a lot of focus on upgrading the facilities, including renovating the Center's main meeting room and the laboratory space on the first floor of building 50.

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1
Fiscal Year
2011
Total Cost
$1,000,000
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Name
National Institute of Arthritis and Musculoskeletal and Skin Diseases
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Lee, Andrew S; Tang, Chad; Rao, Mahendra S et al. (2013) Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies. Nat Med 19:998-1004
Peng, Jun; Liu, Qiuyue; Rao, Mahendra S et al. (2013) Using human pluripotent stem cell-derived dopaminergic neurons to evaluate candidate Parkinson's disease therapeutic agents in MPP+ and rotenone models. J Biomol Screen 18:522-33
Hanson, Charles; Hardarson, Thorir; Ellerstrom, Catharina et al. (2013) Transplantation of human embryonic stem cells onto a partially wounded human cornea in vitro. Acta Ophthalmol 91:127-30
Lomax, Geoffrey P; Hull, Sara Chandros; Lowenthal, Justin et al. (2013) The DISCUSS Project: Induced Pluripotent Stem Cell Lines From Previously Collected Research Biospecimens and Informed Consent: Points to Consider. Stem Cells Transl Med :
Rao, Mahendra (2013) Public private partnerships: a marriage of necessity. Cell Stem Cell 12:149-51
Malik, Nasir; Rao, Mahendra S (2013) A review of the methods for human iPSC derivation. Methods Mol Biol 997:23-33
Pal, Rajarshi; Mamidi, Murali Krishna; Das, Anjan Kumar et al. (2013) Development of a multiplex PCR assay for characterization of embryonic stem cells. Methods Mol Biol 1006:147-66
Shaltouki, Atossa; Peng, Jun; Liu, Qiuyue et al. (2013) Efficient generation of astrocytes from human pluripotent stem cells in defined conditions. Stem Cells 31:941-52
Viswanathan, Sowmya; Rao, Mahendra; Keating, Armand et al. (2013) Overcoming challenges to initiating cell therapy clinical trials in rapidly developing countries: India as a model. Stem Cells Transl Med 2:607-13
Liu, Qiuyue; Pedersen, Oliver Z; Peng, Jun et al. (2013) Optimizing dopaminergic differentiation of pluripotent stem cells for the manufacture of dopaminergic neurons for transplantation. Cytotherapy 15:999-1010

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