The NIH Center for Regenerative Medicine (NIH CRM) represents a new initiative within the intramural program, which is supported by the Common Fund. On August 1, 2011, Mahendra Rao was hired as the first Director of the NIH CRM. His efforts will be shared between the Center and his own lab. Since arriving on campus, Dr. Rao has been orchestrating the renovation and establishment of his lab. We are currently in the process of recruiting laboratory staff (post docs and staff scientists) and purchasing the required tools and reagents to perform our research. There has also been a lot of focus on upgrading the facilities, including renovating the Center's main meeting room and the laboratory space on the first floor of building 50.

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1
Fiscal Year
2011
Total Cost
$1,000,000
Indirect Cost
Name
National Institute of Arthritis and Musculoskeletal and Skin Diseases
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Malik, Nasir; Rao, Mahendra S (2013) A review of the methods for human iPSC derivation. Methods Mol Biol 997:23-33
Pal, Rajarshi; Mamidi, Murali Krishna; Das, Anjan Kumar et al. (2013) Development of a multiplex PCR assay for characterization of embryonic stem cells. Methods Mol Biol 1006:147-66
Shaltouki, Atossa; Peng, Jun; Liu, Qiuyue et al. (2013) Efficient generation of astrocytes from human pluripotent stem cells in defined conditions. Stem Cells 31:941-52
Viswanathan, Sowmya; Rao, Mahendra; Keating, Armand et al. (2013) Overcoming challenges to initiating cell therapy clinical trials in rapidly developing countries: India as a model. Stem Cells Transl Med 2:607-13
Liu, Qiuyue; Pedersen, Oliver Z; Peng, Jun et al. (2013) Optimizing dopaminergic differentiation of pluripotent stem cells for the manufacture of dopaminergic neurons for transplantation. Cytotherapy 15:999-1010
Rao, Mahendra S (2013) LULL(ed) into complacency: a perspective on licenses and stem cell translational science. Stem Cell Res Ther 4:98
Cibelli, Jose; Emborg, Marina E; Prockop, Darwin J et al. (2013) Strategies for improving animal models for regenerative medicine. Cell Stem Cell 12:271-4
Kleitman, Naomi; Rao, Mahendra S; Owens, David F (2013) Pluripotent stem cells in translation: a Food and Drug Administration-National Institutes of Health collaboration. Stem Cells Transl Med 2:483-7
Ren, Yong-Juan; Zhang, Shuming; Mi, Ruifa et al. (2013) Enhanced differentiation of human neural crest stem cells towards the Schwann cell lineage by aligned electrospun fiber matrix. Acta Biomater 9:7727-36
Jiang, Peng; Chen, Chen; Wang, Ruimin et al. (2013) hESC-derived Olig2+ progenitors generate a subtype of astroglia with protective effects against ischaemic brain injury. Nat Commun 4:2196

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