The primary objective of this study remains the same: to link the capabilities of people with and without physical impairments to his or her ability to perform activities of daily living. Many of the methodologies remain the same as well, the core of which is 3D movement analysis. We have collected data on functional movement tasks in both the arm and legs such as reaching and walking in different patient groups, specifically those with cerebral palsy, brachial plexus palsy and adults with dystonia, as well as healthy volunteers, of all ages. This is only an assessment protocol but it has enabled us to evaluate differences in movement or physical assessment characteristics within patient groups as well as between those with and without a specific disorder to provide insights into the mechanisms that underlie motor coordination and how it can be affected by specific conditions. This past year, we have published several papers, two of which were related to walking differences in individuals with cerebral palsy compared to an age-related comparison group and one on quantifying upper limb coordination in persons with and without brachial plexus palsy.

Agency
National Institute of Health (NIH)
Institute
Clinical Center (CLC)
Type
Investigator-Initiated Intramural Research Projects (ZIA)
Project #
1ZIACL060017-27
Application #
9565336
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
27
Fiscal Year
2017
Total Cost
Indirect Cost
Name
Clinical Center
Department
Type
DUNS #
City
State
Country
Zip Code
Oh, Keonyoung; Stanley, Christopher J; Damiano, Diane L et al. (2018) Biomechanical evaluation of virtual reality-based turning on a self-paced linear treadmill. Gait Posture 65:157-162
Mayfield, Christian H; Kukke, Sahana N; Brochard, Sylvain et al. (2017) Inter-joint coordination analysis of reach-to-grasp kinematics in children and adolescents with obstetrical brachial plexus palsy. Clin Biomech (Bristol, Avon) 46:15-22
Bulea, Thomas C; Stanley, Christopher J; Damiano, Diane L (2017) Part 2: Adaptation of Gait Kinematics in Unilateral Cerebral Palsy Demonstrates Preserved Independent Neural Control of Each Limb. Front Hum Neurosci 11:50
Damiano, Diane L; Stanley, Christopher J; Bulea, Thomas C et al. (2017) Motor Learning Abilities Are Similar in Hemiplegic Cerebral Palsy Compared to Controls as Assessed by Adaptation to Unilateral Leg-Weighting during Gait: Part I. Front Hum Neurosci 11:49
Brochard, Sylvain; Alter, Katharine; Damiano, Diane (2014) Shoulder strength profiles in children with and without brachial PLEXUS PALSY. Muscle Nerve 50:60-6
Terry, Kevin; Stanley, Christopher; Damiano, Diane (2014) A new perspective on the walking margin of stability. J Appl Biomech 30:737-41
Damiano, Diane L; Prosser, Laura A; Curatalo, Lindsey A et al. (2013) Muscle plasticity and ankle control after repetitive use of a functional electrical stimulation device for foot drop in cerebral palsy. Neurorehabil Neural Repair 27:200-7
Damiano, Diane L; Wingert, Jason R; Stanley, Christopher J et al. (2013) Contribution of hip joint proprioception to static and dynamic balance in cerebral palsy: a case control study. J Neuroeng Rehabil 10:57
Prosser, Laura A; Curatalo, Lindsey A; Alter, Katharine E et al. (2012) Acceptability and potential effectiveness of a foot drop stimulator in children and adolescents with cerebral palsy. Dev Med Child Neurol 54:1044-9
Moreau, Noelle G; Falvo, Michael J; Damiano, Diane L (2012) Rapid force generation is impaired in cerebral palsy and is related to decreased muscle size and functional mobility. Gait Posture 35:154-8

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