In the past year, we have focused on dissemination of information regarding human urinary exosomes and their use in biomarker discovery studies. This has been done through review articles (see publication list below,) and through information provided on our NHLBI DIR website (Google search: Knepper Systems.) we have also maintained our Urinary Exosome Protein Database (http://dir.nhlbi.nih.gov/papers/lkem/exosome/), which has been a useful resource for the renal research community. Research on urinary exosomes in the nephrology world has exploded. Our original paper (Pisitkun T, Shen RF, Knepper MA. Identification and proteomic profiling of exosomes in human urine. Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13368-73. Epub 2004 Aug 23. PubMed PMID: 153262890) now has almost 500 citations on Scopus. Current work is limited to writing review articles on this topic.
| Chen, Lihe; Lee, Jae Wook; Chou, Chung-Lin et al. (2017) Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq. Proc Natl Acad Sci U S A 114:E9989-E9998 |
| Huebner, Alyssa R; Cheng, Lei; Somparn, Poorichaya et al. (2016) Deubiquitylation of Protein Cargo Is Not an Essential Step in Exosome Formation. Mol Cell Proteomics 15:1556-71 |
| Knepper, Mark A; Kwon, Tae-Hwan; Nielsen, Soren (2015) Molecular Physiology of Water Balance. N Engl J Med 373:196 |
| Knepper, Mark A; Kwon, Tae-Hwan; Nielsen, Soren (2015) Molecular physiology of water balance. N Engl J Med 372:1349-58 |
| Pisitkun, Trairak; Dummer, Patrick; Somparn, Poorichaya et al. (2014) Integrated Design of Antibodies for Systems Biology Using Ab Designer. J Proteomics Bioinform 7:088-94 |
| Yu, Panpan; Pisitkun, Trairak; Wang, Guanghui et al. (2013) Global analysis of neuronal phosphoproteome regulation by chondroitin sulfate proteoglycans. PLoS One 8:e59285 |
| Miller, R Lance; Sandoval, Pablo C; Pisitkun, Trairak et al. (2013) Vasopressin inhibits apoptosis in renal collecting duct cells. Am J Physiol Renal Physiol 304:F177-88 |
| Wilson, Justin L L; Miranda, Carlos A; Knepper, Mark A (2013) Vasopressin and the regulation of aquaporin-2. Clin Exp Nephrol 17:751-64 |
| Knepper, Mark A; Miranda, Carlos A (2013) Urea channel inhibitors: a new functional class of aquaretics. Kidney Int 83:991-3 |
| Zhao, Boyang; Knepper, Mark A; Chou, Chung-Lin et al. (2012) Large-scale phosphotyrosine proteomic profiling of rat renal collecting duct epithelium reveals predominance of proteins involved in cell polarity determination. Am J Physiol Cell Physiol 302:C27-45 |
Showing the most recent 10 out of 37 publications
