Our efforts on the NCS-R study of adults have been significantly reduced over the years, since we have shifted our effort to focus on children and adolescents. However, the NCS-R can be combined with the Adolescent Supplement of the National Comorbidity Study (NCS-A) because the survey instruments were almost identical to those of the NCS-A. During the past year, we have provided consultation on research topics and analyses to several scientists outside the National Institutes of Health. For example, we consulted on a manuscript by a collaborator at Johns Hopkins University on migraine and post-traumatic stress disorder (PTSD) in U.S. adults using NCS-R. The findings indicate that individuals with both migraine and PTSD may be particularly prone to adverse financial, health, and interpersonal disease burdens (Rao et al, in press, Headache). We are also working with a collaborator in Germany to conduct sophisticated analyses of separation anxiety disorder across the life span using both NCS-R (18y+) and NCS-A (13-18y). Public Health Impact: The migraine study has provided important information on links between adverse financial, interpersonal, and health problems as well as migraine comorbidity with PTSD. It may be very useful to guide treatment of migraine in the clinical practice and subsequently ease adverse financial, interpersonal or other health outcomes. Future Plans: We plan to examine family and neighborhood effects on psychopathology using the adolescent/NCS-A and parent/NCS-R paired data. We will continue to work with this rich dataset from the U.S. nationally representative sample to conduct comparative analyses of symptom patterns, correlates and consequences of disorders shown in our parallel adolescent sample.

Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
U.S. National Institute of Mental Health
Zip Code
Rao, Aruna S; Scher, Ann I; Vieira, Rebeca V A et al. (2015) The Impact of Post-Traumatic Stress Disorder on the Burden of Migraine: Results From the National Comorbidity Survey-Replication. Headache 55:1323-41
Peterlin, B Lee; Rosso, Andrea L; Williams, Michelle A et al. (2013) Episodic migraine and obesity and the influence of age, race, and sex. Neurology 81:1314-21
Merikangas, Kathleen R (2013) Contributions of epidemiology to our understanding of migraine. Headache 53:230-46
Lamers, Femke; Burstein, Marcy; He, Jian-ping et al. (2012) Structure of major depressive disorder in adolescents and adults in the US general population. Br J Psychiatry 201:143-50
Merikangas, Kathleen R; McClair, Vetisha L (2012) Epidemiology of substance use disorders. Hum Genet 131:779-89
Fiedorowicz, Jess G; He, Jianping; Merikangas, Kathleen R (2011) The association between mood and anxiety disorders with vascular diseases and risk factors in a nationally representative sample. J Psychosom Res 70:145-54
Lateef, Tarannum; Swanson, Sonja; Cui, Lihong et al. (2011) Headaches and sleep problems among adults in the United States: findings from the National Comorbidity Survey-Replication study. Cephalalgia 31:648-53
Swendsen, Joel; Conway, Kevin P; Degenhardt, Louisa et al. (2010) Mental disorders as risk factors for substance use, abuse and dependence: results from the 10-year follow-up of the National Comorbidity Survey. Addiction 105:1117-28
Nierenberg, A A; Akiskal, H S; Angst, J et al. (2010) Bipolar disorder with frequent mood episodes in the national comorbidity survey replication (NCS-R). Mol Psychiatry 15:1075-87
Angst, Jules; Cui, Lihong; Swendsen, Joel et al. (2010) Major depressive disorder with subthreshold bipolarity in the National Comorbidity Survey Replication. Am J Psychiatry 167:1194-201

Showing the most recent 10 out of 16 publications