During 2009-2010, the Protein Chemistry Core (PCC) provided services to investigators in the NCI-CCR as well as other NIH institutes. In addition, the PCC collaborated with laboratories in the extramural community. 139 samples were processed for N-terminal peptide sequencing. 85 samples were processed for HPLC peptide analysis. 12 samples were processed for peptide digestion. 64 samples were processed for phosphoamino acid analysis. 71 samples were processed for 2D gel electrophoresis. 71 2D-gels were stained or transferred to immobilon for further analysis.
| Sarkar, Tapasree Roy; Sharan, Shikha; Wang, Jun et al. (2012) Identification of a Src tyrosine kinase/SIAH2 E3 ubiquitin ligase pathway that regulates C/EBP? expression and contributes to transformation of breast tumor cells. Mol Cell Biol 32:320-32 |
| Ritt, Daniel A; Monson, Daniel M; Specht, Suzanne I et al. (2010) Impact of feedback phosphorylation and Raf heterodimerization on normal and mutant B-Raf signaling. Mol Cell Biol 30:806-19 |
| Dougherty, Michele K; Ritt, Daniel A; Zhou, Ming et al. (2009) KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals. Mol Cell 34:652-62 |
| McKay, Melissa M; Ritt, Daniel A; Morrison, Deborah K (2009) Signaling dynamics of the KSR1 scaffold complex. Proc Natl Acad Sci U S A 106:11022-7 |
