Agency
National Institute of Health (NIH)
Institute
Office of The Director, National Institutes of Health (OD)
Type
NIH Director’s New Innovator Awards (DP2)
Project #
1DP2OD001378-01
Application #
7426989
Study Section
Special Emphasis Panel (ZGM1-NDIA-G (07))
Program Officer
Basavappa, Ravi
Project Start
2007-09-30
Project End
2012-08-31
Budget Start
2007-09-30
Budget End
2012-08-31
Support Year
1
Fiscal Year
2007
Total Cost
$2,449,750
Indirect Cost
Name
Harvard University
Department
Microbiology/Immun/Virology
Type
Schools of Public Health
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02115
Shell, Scarlet S; Wang, Jing; Lapierre, Pascal et al. (2015) Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape. PLoS Genet 11:e1005641
Ramsdell, Talia L; Huppert, Laura A; Sysoeva, Tatyana A et al. (2015) Linked domain architectures allow for specialization of function in the FtsK/SpoIIIE ATPases of ESX secretion systems. J Mol Biol 427:1119-32
Kester, Jemila C; Fortune, Sarah M (2014) Persisters and beyond: mechanisms of phenotypic drug resistance and drug tolerance in bacteria. Crit Rev Biochem Mol Biol 49:91-101
Lin, Philana Ling; Ford, Christopher B; Coleman, M Teresa et al. (2014) Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing. Nat Med 20:75-9
Shell, Scarlet S; Prestwich, Erin G; Baek, Seung-Hun et al. (2013) DNA methylation impacts gene expression and ensures hypoxic survival of Mycobacterium tuberculosis. PLoS Pathog 9:e1003419
Ragheb, Mark N; Ford, Christopher B; Chase, Michael R et al. (2013) The mutation rate of mycobacterial repetitive unit loci in strains of M. tuberculosis from cynomolgus macaque infection. BMC Genomics 14:145
Fong, Erika J; Sharma, Yasha; Fallica, Brian et al. (2013) Decoupling directed and passive motion in dynamic systems: particle tracking microrheology of sputum. Ann Biomed Eng 41:837-46
Liong, Monty; Hoang, Anh N; Chung, Jaehoon et al. (2013) Magnetic barcode assay for genetic detection of pathogens. Nat Commun 4:1752
Ford, Christopher B; Shah, Rupal R; Maeda, Midori Kato et al. (2013) Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis. Nat Genet 45:784-90
Martin, Constance J; Booty, Matthew G; Rosebrock, Tracy R et al. (2012) Efferocytosis is an innate antibacterial mechanism. Cell Host Microbe 12:289-300

Showing the most recent 10 out of 15 publications