Regulation of GABA-A Receptor Subunit Expression

Grayson, Dennis R.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Modified Research Career Development Award (K04)
• Project #: 5K04NS001647-05
• Application #: 2259658
• Study Section: Neurology C Study Section (NEUC)
• Project Start: 1993-09-01
• Project End: 1998-08-31
• Budget Start: 1996-09-01
• Budget End: 1997-08-31
• Support Year: 5
• Fiscal Year: 1996

Institution

• Name: Allegheny-Singer Research Institute
• DUNS #: 033098401
• City: Pittsburgh
• State: PA
• Country: United States
• Zip Code: 15212

Publications

Shumsky, Jed S; Wu, Yunxing; Murphy, E Hazel et al. (2002) Differential effects of prenatal cocaine exposure on selected subunit mRNAs of the GABA(A) receptor in rabbit anterior cingulate cortex. J Chem Neuroanat 24:243-55

Lauder, J M; Liu, J; Grayson, D R (2000) In utero exposure to serotonergic drugs alters neonatal expression of 5-HT(1A) receptor transcripts: a quantitative RT-PCR study. Int J Dev Neurosci 18:171-6

Vicini, S; Wang, J F; Li, J H et al. (1998) Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors. J Neurophysiol 79:555-66

Grayson, D R; Zhu, W; Harris, B T et al. (1998) Differentially expressed GABAA-receptor subunits result in structurally and functionally receptor assemblies following excitatory afferent synaptic transmission. Perspect Dev Neurobiol 5:193-205

Mizukami, K; Grayson, D R; Ikonomovic, M D et al. (1998) GABAA receptor beta 2 and beta 3 subunits mRNA in the hippocampal formation of aged human brain with Alzheimer-related neuropathology. Brain Res Mol Brain Res 56:268-72

Wang, X H; Zhu, W J; Corsi, L et al. (1998) Chronic dizocilpine (MK-801) reversibly delays GABA(A) receptor maturation in cerebellar granule neurons in vitro. J Neurochem 71:693-704

Shumsky, J S; Wu, Y; Murphy, E H et al. (1998) Prenatal cocaine exposure does not affect selected GABAA receptor subunit mRNA expression in rabbit visual cortex. Ann N Y Acad Sci 846:371-4

Ikonomovic, S; Kharlamov, E; Manev, H et al. (1997) GABA and NMDA in the prevention of apoptotic-like cell death in vitro. Neurochem Int 31:283-90

Liu, J; Morrow, A L; Devaud, L L et al. (1997) Regulation of GABA(A) receptor subunit mRNA expression by the pesticide dieldrin in embryonic brainstem cultures: a quantitative, competitive reverse transcription-polymerase chain reaction study. J Neurosci Res 49:645-53

Fryer, R H; Kaplan, D R; Feinstein, S C et al. (1996) Developmental and mature expression of full-length and truncated TrkB receptors in the rat forebrain. J Comp Neurol 374:21-40