Abstract

Participant enrollment was completed for this project in 8/2015, resulting in a sample of 187 military personnel seeking care for a sleep disorder or who served as healthy controls. All participants in this study underwent a polysomonographic sleep evlauation and had blood collected for biomarker measurement which includes proteomics, gene-expression and DNA methyltion. Participants are seen at baseline and then 6 weeks following this. We use follow-up data to examine changes in symptoms with standard of care interventions.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Nursing Research (NINR)
Type
Investigator-Initiated Intramural Research Projects (ZIA)
Project #
1ZIANR000027-03
Application #
9148051
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
2015
Total Cost
Indirect Cost

  Institution

Name
National Institute of Nursing Research
Department
Type
DUNS #
City
State
Country
Zip Code

  Publications

Osier, Nicole; Motamedi, Vida; Edwards, Katie et al. (2018) Exosomes in Acquired Neurological Disorders: New Insights into Pathophysiology and Treatment. Mol Neurobiol :
Motamedi, Vida; Kanefsky, Rebekah; Matsangas, Panagiotis et al. (2018) Elevated tau and interleukin-6 concentrations in adults with obstructive sleep apnea. Sleep Med 43:71-76
Devoto, Christina; Arcurio, Lindsay; Fetta, Joseph et al. (2017) Inflammation Relates to Chronic Behavioral and Neurological Symptoms in Military Personnel with Traumatic Brain Injuries. Cell Transplant 26:1169-1177
Martin, Christiana G; Kim, Hyungsuk; Yun, Sijung et al. (2017) Circulating miRNA associated with posttraumatic stress disorder in a cohort of military combat veterans. Psychiatry Res 251:261-265
Cashion, Ann K; Gill, Jessica; Hawes, Rebecca et al. (2016) National Institutes of Health Symptom Science Model sheds light on patient symptoms. Nurs Outlook 64:499-506
Devoto, Christina; Arcurio, Lindsay; Fetta, Joseph et al. (2016) Inflammation Relates to Chronic Behavioral and Neurological Symptoms in Military with Traumatic Brain Injuries. Cell Transplant :
Rusch, Heather L; Guardado, Pedro; Baxter, Tristin et al. (2015) Improved Sleep Quality is Associated with Reductions in Depression and PTSD Arousal Symptoms and Increases in IGF-1 Concentrations. J Clin Sleep Med 11:615-23
Mysliwiec, Vincent; Gill, Jessica; Matsangas, Panagiotis et al. (2015) IGF-1: a potential biomarker for efficacy of sleep improvement with automatic airway pressure therapy for obstructive sleep apnea? Sleep Breath :
Roy, Michael J; Costanzo, Michelle; Gill, Jessica et al. (2015) Predictors of Neurocognitive Syndromes in Combat Veterans. Cureus 7:e293
Gill, Jessica M; Lee, Hyunhwa; Baxter, Tristin et al. (2015) A Diagnosis of Insomnia Is Associated With Differential Expression of Sleep-Regulating Genes in Military Personnel. Biol Res Nurs 17:384-92

Showing the most recent 10 out of 23 publications