Abstract

The overall goal of the collaboration efforts of the Yeast Resource Center is to continue refining technologies developed within the center while simultaneously providing access to expertise and resources to the scientific community. Our resource has been an invaluable collaborative resource for the scientific community by making available advanced technologies developed by the center. In the last 5 years our Biomedical Technology Research Resource (BTRR) has had a total of 347 collaborations that are widely distributed throughout the United States. Collaborations differ from our Driving Biomedical Projects in that they don't require the development of new technologies but instead directly apply more established methods that make use of the expertise, instrumentation, software, and protocols facilitated by our resource. We have a history of openly supporting the scientific community by accepting collaborations that align with our expertise. A strength of a ?Yeast? resource center is that we have been a valuable resource and source of collaboration for the yeast scientific community. These collaborations have become an excellent opportunity in refining our established technologies. Once refined, methods often get extended to collaborations in experimental systems beyond yeast as the technology matures.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Biotechnology Resource Grants (P41)
Project #
2P41GM103533-21
Application #
9208075
Study Section
Special Emphasis Panel (ZRG1)
Project Start
1997-09-30
Project End
2022-03-31
Budget Start
2017-01-01
Budget End
2017-12-31
Support Year
21
Fiscal Year
2017
Total Cost
Indirect Cost

  Institution

Name
University of Washington
Department
Biochemistry
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Helgeson, Luke A; Zelter, Alex; Riffle, Michael et al. (2018) Human Ska complex and Ndc80 complex interact to form a load-bearing assembly that strengthens kinetochore-microtubule attachments. Proc Natl Acad Sci U S A 115:2740-2745
Fong, Kimberly K; Zelter, Alex; Graczyk, Beth et al. (2018) Novel phosphorylation states of the yeast spindle pole body. Biol Open 7:
González, Delfina P; Lamb, Helen V; Partida, Diana et al. (2018) CBD-1 organizes two independent complexes required for eggshell vitelline layer formation and egg activation in C. elegans. Dev Biol 442:288-300
Basisty, Nathan B; Liu, Yuxin; Reynolds, Jason et al. (2018) Stable Isotope Labeling Reveals Novel Insights Into Ubiquitin-Mediated Protein Aggregation With Age, Calorie Restriction, and Rapamycin Treatment. J Gerontol A Biol Sci Med Sci 73:561-570
Brandsen, Benjamin M; Mattheisen, Jordan M; Noel, Teia et al. (2018) A Biosensor Strategy for E. coli Based on Ligand-Dependent Stabilization. ACS Synth Biol 7:1990-1999
Ma, Yuanhui; Yates 3rd, John R (2018) Proteomics and pulse azidohomoalanine labeling of newly synthesized proteins: what are the potential applications? Expert Rev Proteomics 15:545-554
Tseng, Boo Shan; Reichhardt, Courtney; Merrihew, Gennifer E et al. (2018) A Biofilm Matrix-Associated Protease Inhibitor Protects Pseudomonas aeruginosa from Proteolytic Attack. MBio 9:
Yates 3rd, John R (2018) Content Is King: Databases Preserve the Collective Information of Science. J Biomol Tech 29:1-3
DaRosa, Paul A; Harrison, Joseph S; Zelter, Alex et al. (2018) A Bifunctional Role for the UHRF1 UBL Domain in the Control of Hemi-methylated DNA-Dependent Histone Ubiquitylation. Mol Cell 72:753-765.e6
Xu, Yi; Ju, Ho-Jong; DeBlasio, Stacy et al. (2018) A Stem-Loop Structure in Potato Leafroll Virus Open Reading Frame 5 (ORF5) Is Essential for Readthrough Translation of the Coat Protein ORF Stop Codon 700 Bases Upstream. J Virol 92:

Showing the most recent 10 out of 372 publications