The goal of the Data Management Core is to provide an integrated data management and statistical consultation platform for the Cores and Projects in this ADRC and to serve as a provider and an end user for the NACC. The data management team receives, stores, catalogues, tracks and integrates all data generated by the Cores and, when appropriate. Projects, in this ADRC and provides expert advice for the statistical analysis of the existing data and for the design of new studies generated from this ADRC. The data management team also maintains a smooth channel of data submission and data checking for the NACC. The data handling goal will be accomplished by using the specifically designed and well established data warehouse system within the Department of Psychiatry. This system provides access to the contributing projects within the ADRC and the related projects within the Department to integrated data acquisition, storage and query capacity. Because the data warehouse is implemented across multiple projects department-wide, it provides for data access not only to data derived by the specific projects and cores within the ADRC but also to data being derived, and previously acquired legacy data, by many related projects within the Department of Psychiatry network. Most routine data management procedures, such as data entry, logical check and data summary report can be performed automatically with this system. Another mission of the Data Management Core is to provide statistical support to the other Cores and the Projects. The statistical analysis of data generating from the Cores and Projects and the experimental design of new pilot projects in this ADRC are supervised by the Core PI, Dr. Xiaodong Luo and the statistician. Dr. James Schmeidler, who have participated in the planning of the studies and will provide ongoing support throughout the execution of the projects.

Public Health Relevance

The Data Management Core helps smooth and enhance the overall effort of this ADRC in colleting and analyzing data. The Core will work closely with the other Cores and Projects in this ADRC in order to better understand the data.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
5P50AG005138-27
Application #
8440472
Study Section
Special Emphasis Panel (ZAG1-ZIJ-4)
Project Start
1997-05-01
Project End
2015-03-31
Budget Start
2011-04-01
Budget End
2012-03-31
Support Year
27
Fiscal Year
2011
Total Cost
$139,599
Indirect Cost
Name
Icahn School of Medicine at Mount Sinai
Department
Type
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029
Sano, Mary; Zhu, Carolyn W; Grossman, Hillel et al. (2017) Longitudinal Cognitive Profiles in Diabetes: Results From the National Alzheimer's Coordinating Center's Uniform Data. J Am Geriatr Soc 65:2198-2204
Tripodis, Yorghos; Alosco, Michael L; Zirogiannis, Nikolaos et al. (2017) The Effect of Traumatic Brain Injury History with Loss of Consciousness on Rate of Cognitive Decline Among Older Adults with Normal Cognition and Alzheimer's Disease Dementia. J Alzheimers Dis 59:251-263
Brenowitz, Willa D; Hubbard, Rebecca A; Keene, C Dirk et al. (2017) Mixed neuropathologies and estimated rates of clinical progression in a large autopsy sample. Alzheimers Dement 13:654-662
Jutkowitz, Eric; Kane, Robert L; Gaugler, Joseph E et al. (2017) Societal and Family Lifetime Cost of Dementia: Implications for Policy. J Am Geriatr Soc 65:2169-2175
Livny, Abigail; Ravona-Springer, Ramit; Heymann, Anthony et al. (2017) Haptoglobin 1-1 Genotype Modulates the Association of Glycemic Control With Hippocampal Volume in Elderly Individuals With Type 2 Diabetes. Diabetes 66:2927-2932
Moheb, Negar; Mendez, Mario F; Kremen, Sarah A et al. (2017) Executive Dysfunction and Behavioral Symptoms Are Associated with Deficits in Instrumental Activities of Daily Living in Frontotemporal Dementia. Dement Geriatr Cogn Disord 43:89-99
Monsell, Sarah E; Mock, Charles; Fardo, David W et al. (2017) Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology. Alzheimer Dis Assoc Disord 31:232-238
Jiang, Yan; Loh, Yong-Hwee Eddie; Rajarajan, Prashanth et al. (2017) The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. Nat Genet 49:1239-1250
Kaur, G; Pawlik, M; Gandy, S E et al. (2017) Lysosomal dysfunction in the brain of a mouse model with intraneuronal accumulation of carboxyl terminal fragments of the amyloid precursor protein. Mol Psychiatry 22:981-989
Mez, Jesse; Chung, Jaeyoon; Jun, Gyungah et al. (2017) Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans. Alzheimers Dement 13:119-129

Showing the most recent 10 out of 463 publications