This application proposes to conduct a Stage II randomized trial to test Culturally Informed &Flexible Family-Based Treatment for Adolescents (CIFFTA) a treatment developed as part of a Stage I treatment development effort and showing very promising preliminary findings. Drug use rate are highest among Hispanic middle school youth and to date there are few if any treatments that have been proven effective with substance abusing Hispanic adolescents. Further treatment for Hispanic youth and families is complicated by the fact that these families often differ from mainstream drug users in values, beliefs and behaviors that can directly impact engagement, retention, and efficacy/effectiveness of drug treatment. Our efforts to develop and fully test a more powerful treatment that can address these issues began with a Stage 1 study that: 1) led to the development of a flexible manual that allows treatment tailoring to the unique family characteristics, 2) showed highly promising feasibility and acceptability indicators (Santisteban and Mena, in press) and 3) showed highly promising preliminary outcomes on both drug use and family-level hypothesized mediators (Santisteban et al., unpublished manuscript). This application proposes a Stage II randomized trial with 220 Hispanic youngsters'ages 14-17 meeting criteria for drug abuse and their families. The study will test the treatment's efficacy compared to a control condition, in impacting drug use, risky sexual behavior, and hypothesized mechanisms (family functioning and therapeutic alliance) of change, in a larger and more rigorous trial. The study also includes a test of the dose-response relationship and exploration of moderators of treatment outcome. This application responds to a Program Announcement (PA-07-111) that outlines as areas of interest """"""""...women, minorities, families, couples, specific cultural groups, adolescents..."""""""" The Stage II trial focuses on a treatment designed to boost the treatment effects by building in a flexible tailoring process to better address the specific needs of: 1) adolescents, 2) minorities and a special cultural group - Hispanics, via a treatment that works with 3) couples and families.

Public Health Relevance

Should this line of research continue to be successful, it will contribute to the field: 1) a highly innovative and effective treatment for Hispanic drug abusing adolescents, 2) a better understanding of the mechanisms of change in family therapy with drug abusing adolescents, and 3) a framework for flexible and tailored treatment that can be used to better address the unique needs of other special populations.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA027920-03
Application #
8257579
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Chambers, Jessica Campbell
Project Start
2010-04-01
Project End
2015-03-31
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
3
Fiscal Year
2012
Total Cost
$597,626
Indirect Cost
$165,972
Name
University of Miami Coral Gables
Department
Type
Schools of Nursing
DUNS #
625174149
City
Coral Gables
State
FL
Country
United States
Zip Code
33146
Stanforth, Evan T; McCabe, Brian E; Mena, Maite P et al. (2016) Structure of Problem Recognition Questionnaire with Hispanic/Latino Adolescents. J Subst Abuse Treat 71:36-40
Santisteban, Daniel A; Mena, Maite P; Muir, Joan et al. (2015) The efficacy of two adolescent substance abuse treatments and the impact of comorbid depression: results of a small randomized controlled trial. Psychiatr Rehabil J 38:55-64
McCabe, Brian E; Santisteban, Daniel A; Mena, Maite P et al. (2013) Engagement, retention, and abstinence for three types of opioid users in Florida. Subst Use Misuse 48:623-34
Santisteban, Daniel A; Coatsworth, J Douglas; Briones, Ervin et al. (2012) Beyond acculturation: an investigation of the relationship of familism and parenting to behavior problems in Hispanic youth. Fam Process 51:470-82
Santisteban, Daniel A; Mena, Maite P; Abalo, Clara (2012) Bridging Diversity and Family Systems: Culturally Informed and Flexible Family Based Treatment for Hispanic Adolescents. Couple Family Psychol 2:246-263
Santisteban, Daniel A; Mena, Maite P; McCabe, Brian E (2011) Preliminary results for an adaptive family treatment for drug abuse in Hispanic youth. J Fam Psychol 25:610-4