A critical requirement for the future of outstanding health care in the United States is the training of physician-scientists who will investigate fundamental basic science questions which ultimately relate to clinical problems. The mission of the M.D./Ph.D. program of Mayo Medical and Graduate Schools is to train a small number of gifted students in the methods, tools and disciplines of the laboratory basic scientist, while also helping them develop skills for relieving human suffering. The faculty for the Mayo MSTP will include 57 of the most highly productive, well-funded research scientists at the Mayo Clinic with demonstrated abilities for mentoring young scientists. The seamless integration of the M.D./Ph.D. program between Mayo Medical School and Mayo Graduate School parallels the complete integration of basic research and clinical investigation at Mayo. These collaborations among Ph.D. scientists and physician scientists model the future careers for M.D./Ph.D. students. The Mayo M.D./Ph.D. program enrolls approximately 6 new students each year in a medical school class o 42. M.D./Ph.D. students are selected from an annual applicant pool of about 150 of the most talented future physician scientists in the country. During their M.D./Ph.D. training they mature into highly productive basic scientists. The integrated basic science core curriculum and programmatic approach to research allows flexible access to an outstanding selection of research faculty as mentors for Mayo MSTP students. Although this is a relatively young program, 39 students have graduated and 36 are currently enrolled. Graduates are continuing on toward successful careers and continuing to make significant scientific contributions. As an NIGMS-designated MSTP the Mayo program will be able to further improve and increase its impact on the training of much-needed physician scientists prepared to apply the explosive growth in biomedical information to important clinical problems.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
1T32GM065841-01
Application #
6505396
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Shapiro, Bert I
Project Start
2003-07-01
Project End
2008-06-30
Budget Start
2003-07-01
Budget End
2004-06-30
Support Year
1
Fiscal Year
2003
Total Cost
$92,043
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
006471700
City
Rochester
State
MN
Country
United States
Zip Code
55905
Wilton, Katelynn M; Matteson, Eric L (2017) Malignancy Incidence, Management, and Prevention in Patients with Rheumatoid Arthritis. Rheumatol Ther 4:333-347
Dudenkov, Tanda M; Ingle, James N; Buzdar, Aman U et al. (2017) SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway. Breast Cancer Res Treat 164:189-199
Knorr, Katherine L B; Finn, Laura E; Smith, B Douglas et al. (2017) Assessment of Drug Sensitivity in Hematopoietic Stem and Progenitor Cells from Acute Myelogenous Leukemia and Myelodysplastic Syndrome Ex Vivo. Stem Cells Transl Med 6:840-850
Shim, Kevin G; Zaidi, Shane; Thompson, Jill et al. (2017) Inhibitory Receptors Induced by VSV Viroimmunotherapy Are Not Necessarily Targets for Improving Treatment Efficacy. Mol Ther 25:962-975
Wyles, S P; Hrstka, S C; Reyes, S et al. (2016) Pharmacological Modulation of Calcium Homeostasis in Familial Dilated Cardiomyopathy: An In Vitro Analysis From an RBM20 Patient-Derived iPSC Model. Clin Transl Sci 9:158-67
Pratz, Keith W; Koh, Brian D; Patel, Anand G et al. (2016) Poly (ADP-Ribose) Polymerase Inhibitor Hypersensitivity in Aggressive Myeloproliferative Neoplasms. Clin Cancer Res 22:3894-902
Kottke, Tim; Shim, Kevin G; Alonso-Camino, Vanesa et al. (2016) Immunogenicity of self tumor associated proteins is enhanced through protein truncation. Mol Ther Oncolytics 3:16030
Weaver, Robbyn L; Limzerwala, Jazeel F; Naylor, Ryan M et al. (2016) BubR1 alterations that reinforce mitotic surveillance act against aneuploidy and cancer. Elife 5:
Yun, Seongseok; Vincelette, Nicole D; Knorr, Katherine L B et al. (2016) 4EBP1/c-MYC/PUMA and NF-?B/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells. Blood 127:2711-22
Ranatunga, Wasantha; Gakh, Oleksandr; Galeano, Belinda K et al. (2016) Architecture of the Yeast Mitochondrial Iron-Sulfur Cluster Assembly Machinery: THE SUB-COMPLEX FORMED BY THE IRON DONOR, Yfh1 PROTEIN, AND THE SCAFFOLD, Isu1 PROTEIN. J Biol Chem 291:10378-98

Showing the most recent 10 out of 93 publications