Center activities will be spread out across 6 Cores, each one with a designated Core Director (director names in parentheses): Core 1 - Theoretical and Computational Studies (Barry Honig);Core 2 - Driving Biological projects (Andrea Califano);Core 3 - Infrastructure (J.Wofford);Core 4 - Education (D.Vitkup);Core 5 - Dissemination (A.FIoratos);Core 6 - Administration (A.Califano). Activities within Core 1 and Core 2 have been further grouped into 4 Projects and 3 DBPs, each one with a designated leader. The multi-Core and multi-project nature of the Center makes it imperative to establish an efficient and competent management structure that will be able to effectively coordinate activities within and across cores. Having successfully run the MAGNet Center for 5 years, we already have in place established and proven procedures which will serve as the basis for carrying out the mission of the Core.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA121852-10
Application #
8707395
Study Section
Special Emphasis Panel (ZRG1-BST-K)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
10
Fiscal Year
2014
Total Cost
$397,585
Indirect Cost
$225,771
Name
Columbia University (N.Y.)
Department
Type
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032
Kushwaha, Ritu; Jagadish, Nirmala; Kustagi, Manjunath et al. (2015) Interrogation of a context-specific transcription factor network identifies novel regulators of pluripotency. Stem Cells 33:367-77
Sanchez-Garcia, FĂ©lix; Villagrasa, Patricia; Matsui, Junji et al. (2014) Integration of genomic data enables selective discovery of breast cancer drivers. Cell 159:1461-75
Messina, Monica; Del Giudice, Ilaria; Khiabanian, Hossein et al. (2014) Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness. Blood 123:2378-88
Lee, Eunjee; de Ridder, Jeroen; Kool, Jaap et al. (2014) Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis. Proc Natl Acad Sci U S A 111:5747-52
Sonabend, Adam M; Carminucci, Arthur S; Amendolara, Benjamin et al. (2014) Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma. Neuro Oncol 16:1210-9
van Arensbergen, Joris; van Steensel, Bas; Bussemaker, Harmen J (2014) In search of the determinants of enhancer-promoter interaction specificity. Trends Cell Biol 24:695-702
Repunte-Canonigo, Vez; Lefebvre, Celine; George, Olivier et al. (2014) Gene expression changes consistent with neuroAIDS and impaired working memory in HIV-1 transgenic rats. Mol Neurodegener 9:26
Johnson, Stephanie; van de Meent, Jan-Willem; Phillips, Rob et al. (2014) Multiple LacI-mediated loops revealed by Bayesian statistics and tethered particle motion. Nucleic Acids Res 42:10265-77
Pefanis, Evangelos; Wang, Jiguang; Rothschild, Gerson et al. (2014) Noncoding RNA transcription targets AID to divergently transcribed loci in B cells. Nature 514:389-93
Ward, Lucas D; Wang, Junbai; Bussemaker, Harmen J (2014) Characterizing a collective and dynamic component of chromatin immunoprecipitation enrichment profiles in yeast. BMC Genomics 15:494

Showing the most recent 10 out of 178 publications