? Pilot Projects One pilot project will be funded per year, beginning in Year 2 of the award. The purpose of these projects will be to conduct translational research in Barrett's esophagus that meets the objectives of the BETRNet, falls within one of the four designated Research Areas, and that can utilize effectively the resources available through our integrated Research Center. Cross-BETRNet Activities One Cross-BETRNet project will be funded per year, beginning in Year 2 of the award. The purpose of these projects will be to conduct translational research in Barrett's esophagus that meets the objectives of the BETRNet, falls within one of the four designated Research Areas, and that can feasibly utilize the resources available through our Research Center in combination with the other BETRNet consortia. The below outlined application details will be modified as needed based on guidelines set forth by the BETRNet Steering Committee. In order to minimize duplicated effort, much of the organization, administration, and oversight for Cross-BETRNet Projects is similar to that described above for the Pilot Projects. Additionally, we have commitment from other BETRNet Consortium applicants regarding potential future cross-BETRNet collaborative efforts (see Section 2.7. Letters of Commitment).

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA163004-03
Application #
8535700
Study Section
Special Emphasis Panel (ZCA1-SRLB-1)
Project Start
Project End
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
3
Fiscal Year
2013
Total Cost
$169,165
Indirect Cost
$49,422
Name
Columbia University (N.Y.)
Department
Type
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032
Abrams, Julian A; Appelman, Henry D; Beer, David G et al. (2014) Barrett's Esophagus Translational Research Network (BETRNet): the pivotal role of multi-institutional collaboration in esophageal adenocarcinoma research. Gastroenterology 146:1586-90
Fudman, David I; Lightdale, Charles J; Poneros, John M et al. (2014) Positive correlation between endoscopist radiofrequency ablation volume and response rates in Barrett's esophagus. Gastrointest Endosc 80:71-7
Freedberg, Daniel E; Abrams, Julian A; Wang, Timothy C (2014) Prevention of gastric cancer with antibiotics: can it be done without eradicating Helicobacter pylori? J Natl Cancer Inst 106:
Hartman, Kira G; Bortner Jr, James D; Falk, Gary W et al. (2014) Modeling human gastrointestinal inflammatory diseases using microphysiological culture systems. Exp Biol Med (Maywood) 239:1108-23
Timmer, M R; Sun, G; Gorospe, E C et al. (2013) Predictive biomarkers for Barrett's esophagus: so near and yet so far. Dis Esophagus 26:574-81
Gupta, Milli; Iyer, Prasad G; Lutzke, Lori et al. (2013) Recurrence of esophageal intestinal metaplasia after endoscopic mucosal resection and radiofrequency ablation of Barrett's esophagus: results from a US Multicenter Consortium. Gastroenterology 145:79-86.e1
Tomizawa, Yutaka; Iyer, Prasad G; Wong Kee Song, Louis M et al. (2013) Safety of endoscopic mucosal resection for Barrett's esophagus. Am J Gastroenterol 108:1440-7; quiz 1448
Wang, Kenneth K (2013) The essence of management of Barrett's esophagus. Gastrointest Endosc 78:702-3
Quante, Michael; Abrams, Julian A; Wang, Timothy C (2013) The rapid rise in gastroesophageal junction tumors: is inflammation of the gastric cardia the underwater iceberg? Gastroenterology 145:708-11
Leggett, Cadman L; Gorospe, Emmanuel C; Wang, Kenneth K (2013) Endoscopic therapy for Barrett's esophagus and early esophageal adenocarcinoma. Gastroenterol Clin North Am 42:175-85

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