The Malaria Research and Training Program in Zimbabwe (MRTPZ) will link the research and educational opportunities of the Molecular Microbiology and Immunology (MMI) Department of the Johns Hopkins School of Public Health with the internationally known Blair Research Institute (BRI) and the Biomedical Research and Training Institute (BRTI) for the purpose of invigorating the existing malaria prevention and control infrastructure of Zimbabwe. The long-term objective will be to fortify and sustain a center of excellence in an African malaria endemic setting. The MRTPZ will knit comprehensive research training of two pre-doctoral and two masters level students at MMI with home country education training in immunologic aspects of malaria transmission control, characterization of drug resistance patterns, vector control strategies, community involvement in malaria control and research methods training. The BRI is the lead government agency charged with management of scientific research and training on Zimbabwe health problems. Malaria control is one of the three priority areas in the national health strategy. The Department of MMI conducts research and trains scientists in the basic mechanisms of infectious diseases and host responses with the underlying School of Public Health philosophy that employs state-of-the-art scientific approaches to public health problems of global significance. The malaria research projects, initiated at MMI but conducted in Zimbabwe will provide a structure for the application of theoretical knowledge gained from comprehensive courses in molecular biology, microbiology, immunology, ecology and-population genetics to the issues related to malaria epidemiology, vector biology, immunology and vaccines, anti malaria drugs, pathogenesis and health systems and operational methods. An essential aspect of the training program, includes a requirement to participate in seminars, research forums, journal clubs, national and international scientific meetings and to participate in the various training courses to be offered in Zimbabwe jointly by the faculty from Hopkins, BRI and BRTI. The training program will be structured to meet the program goals and closely supervised by the MRTPZ advisory committee.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
5D43TW001587-04
Application #
6637736
Study Section
Special Emphasis Panel (ZAI1-ALR-F (S4))
Program Officer
Sina, Barbara J
Project Start
2000-09-29
Project End
2005-02-28
Budget Start
2003-03-01
Budget End
2004-02-29
Support Year
4
Fiscal Year
2003
Total Cost
$144,751
Indirect Cost
Name
Johns Hopkins University
Department
Microbiology/Immun/Virology
Type
Schools of Public Health
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Reid, Tsungai; Munyanyi, Merjury; Mduluza, Takafira (2017) Effect of cooking and preservation on nutritional and phytochemical composition of the mushroom Amanita zambiana. Food Sci Nutr 5:538-544
Ellekvist, Peter; Mlambo, Godfree; Kumar, Nirbhay et al. (2017) Functional characterization of malaria parasites deficient in the K+ channel Kch2. Biochem Biophys Res Commun 493:690-696
Bansal, Geetha P; Vengesai, Arthur; Cao, Yi et al. (2017) Antibodies elicited during natural infection in a predominantly Plasmodium falciparum transmission area cross-react with sexual stage-specific antigen in P. vivax. Acta Trop 170:105-111
Paul, Noah H; Vengesai, Arthur; Mduluza, Takafira et al. (2016) Prevalence of Plasmodium falciparum transmission reducing immunity among primary school children in a malaria moderate transmission region in Zimbabwe. Acta Trop 163:103-8
Laban, Natasha M; Kobayashi, Tamaki; Hamapumbu, Harry et al. (2015) Comparison of a PfHRP2-based rapid diagnostic test and PCR for malaria in a low prevalence setting in rural southern Zambia: implications for elimination. Malar J 14:25
Sitali, Lungowe; Chipeta, James; Miller, John M et al. (2015) Patterns of mixed Plasmodium species infections among children six years and under in selected malaria hyper-endemic communities of Zambia: population-based survey observations. BMC Infect Dis 15:204
Siame, Mwiche N P; Mharakurwa, Sungano; Chipeta, James et al. (2015) High prevalence of dhfr and dhps molecular markers in Plasmodium falciparum in pregnant women of Nchelenge district, Northern Zambia. Malar J 14:190
Norris, Laura C; Norris, Douglas E (2013) Heterogeneity and changes in inequality of malaria risk after introduction of insecticide-treated bed nets in Macha, Zambia. Am J Trop Med Hyg 88:710-7
Fornadel, Christen M; Norris, Laura C; Franco, Veronica et al. (2011) Unexpected anthropophily in the potential secondary malaria vectors Anopheles coustani s.l. and Anopheles squamosus in Macha, Zambia. Vector Borne Zoonotic Dis 11:1173-9
Fornadel, Christen M; Norris, Laura C; Glass, Gregory E et al. (2010) Analysis of Anopheles arabiensis blood feeding behavior in southern Zambia during the two years after introduction of insecticide-treated bed nets. Am J Trop Med Hyg 83:848-53

Showing the most recent 10 out of 13 publications