The long-term objective of the Malaria Training and Research Capacity Building in Southern Africa is to create a center of excellence for malaria research in Southern Africa. The proposed program builds upon our previous success with the Malaria Research and Training Program in Zimbabwe. We propose to continue to strengthen our current trainees (two PhD) while extending malaria research and training to Zambia and neighboring Southern African countries. In addition to maintaining strong research ties with our former trainees, we propose to create specific training to satisfy immediate needs of the local research community. This would occur in the form of short-term training in state-of-the-art research methods and techniques offered by Johns Hopkins faculty. In addition, four different training courses will be offered in Zambia: (1) Plasmodium Biology and Treatment, (2) Malaria Control: Monitoring and Evaluation, (3) Basic Immunology and Microbial Immunity and (4) Entomology. The courses will be offered in partnership between Johns Hopkins University faculty and scientists from various centers in Zambia, especially the School of Medicine University Teaching Hospital, University of Zambia, Malaria Institute at Macha and Tropical Disease Research Center at Ndola. These courses will also involve our former training grant colleagues from Zimbabwe. The various malaria research and training activities conducted in Zambia will provide a structure for the application of knowledge gained from training courses and specialized targeted research training in molecular biology, microbiology, immunology, ecology, molecular epidemiology, genomics and population genetics to local issues resulting in the creation of a comprehensive research community of more than a dozen scientists in the region.

National Institute of Health (NIH)
Fogarty International Center (FIC)
International Research Training Grants (D43)
Project #
Application #
Study Section
Special Emphasis Panel (ZRG1-ICP2-B (51))
Program Officer
Sina, Barbara J
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Tulane University
Internal Medicine/Medicine
Schools of Public Health
New Orleans
United States
Zip Code
Reid, Tsungai; Munyanyi, Merjury; Mduluza, Takafira (2017) Effect of cooking and preservation on nutritional and phytochemical composition of the mushroom Amanita zambiana. Food Sci Nutr 5:538-544
Ellekvist, Peter; Mlambo, Godfree; Kumar, Nirbhay et al. (2017) Functional characterization of malaria parasites deficient in the K+ channel Kch2. Biochem Biophys Res Commun 493:690-696
Bansal, Geetha P; Vengesai, Arthur; Cao, Yi et al. (2017) Antibodies elicited during natural infection in a predominantly Plasmodium falciparum transmission area cross-react with sexual stage-specific antigen in P. vivax. Acta Trop 170:105-111
Paul, Noah H; Vengesai, Arthur; Mduluza, Takafira et al. (2016) Prevalence of Plasmodium falciparum transmission reducing immunity among primary school children in a malaria moderate transmission region in Zimbabwe. Acta Trop 163:103-8
Laban, Natasha M; Kobayashi, Tamaki; Hamapumbu, Harry et al. (2015) Comparison of a PfHRP2-based rapid diagnostic test and PCR for malaria in a low prevalence setting in rural southern Zambia: implications for elimination. Malar J 14:25
Sitali, Lungowe; Chipeta, James; Miller, John M et al. (2015) Patterns of mixed Plasmodium species infections among children six years and under in selected malaria hyper-endemic communities of Zambia: population-based survey observations. BMC Infect Dis 15:204
Siame, Mwiche N P; Mharakurwa, Sungano; Chipeta, James et al. (2015) High prevalence of dhfr and dhps molecular markers in Plasmodium falciparum in pregnant women of Nchelenge district, Northern Zambia. Malar J 14:190
Norris, Laura C; Norris, Douglas E (2013) Heterogeneity and changes in inequality of malaria risk after introduction of insecticide-treated bed nets in Macha, Zambia. Am J Trop Med Hyg 88:710-7
Fornadel, Christen M; Norris, Laura C; Franco, Veronica et al. (2011) Unexpected anthropophily in the potential secondary malaria vectors Anopheles coustani s.l. and Anopheles squamosus in Macha, Zambia. Vector Borne Zoonotic Dis 11:1173-9
Fornadel, Christen M; Norris, Laura C; Glass, Gregory E et al. (2010) Analysis of Anopheles arabiensis blood feeding behavior in southern Zambia during the two years after introduction of insecticide-treated bed nets. Am J Trop Med Hyg 83:848-53

Showing the most recent 10 out of 13 publications