The applicant's proposed research is an exploration of the barriers that influence adherence to antiretroviral therapy (ART) by HIV-positive individuals who use illicit drugs. Twenty years of research suggest that patient characteristics, provider factors, treatment regimen factors, and social/environmental factors play a role in chronic disease treatment compliance. However, few studies have explicitly linked these factors to non-adherence among HIV-positive individuals who use illicit drugs. The proposed study aims to study the impact of these potential barriers through a mixed method design: secondary analysis of the HIV Cost and Services Utilization Study (HCSUS) and content analysis of the Participating and Communicating Together Study (PACT). This information can be used to strengthen medication adherence interventions for HIV positive drug using populations. Moreover, because drug-related HIV/AIDS disproportionately affects African Americans and other communities of color, research that leads to improvements in HIV treatment outcomes for drug-using populations may also help reduce racial/ethnic health disparities.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
1F31AI058913-01
Application #
6746693
Study Section
Special Emphasis Panel (ZRG1-SSS-C (29))
Program Officer
Hernandez, Milton J
Project Start
2004-06-01
Project End
2007-05-31
Budget Start
2004-06-01
Budget End
2005-05-31
Support Year
1
Fiscal Year
2004
Total Cost
$36,862
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Miscellaneous
Type
Schools of Public Health
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Thrasher, Angela D; Earp, Jo Anne L; Golin, Carol E et al. (2008) Discrimination, distrust, and racial/ethnic disparities in antiretroviral therapy adherence among a national sample of HIV-infected patients. J Acquir Immune Defic Syndr 49:84-93