? Past work has demonstrated that level of cocaine use in heroin-dependent individuals is positively related to increased engagement in HIV-risk taking behaviors. Although the results are promicint, several limitations need to be addressed. A true test would require more separable groups of crack/cocaine and heroin users, to more clearly isolate differences among these drugs. Thus, in the current application we further examine the relationship between cocaine use and HIV-risk taking behaviors, and including a focus on the role of impulsivity-related factors as pathways to drug choice. Specifically, we will study 100 drug users seeking treatment to examine the following: a) differences in risky sexual behavior and HIV risk behaviors across drug groups, and b) the relationship between various constructs of disinhibition to drug preference. Following from these initial results, we will retest participants after treatment to begin to examine the time course of drug use and risky sexual behavior, and its influence on risky sexual behavior after treatment across heroin and crack/cocaine users. ? ? ? ?
| Bornovalova, Marina A; Gwadz, Marya A; Kahler, Christopher et al. (2008) Sensation seeking and risk-taking propensity as mediators in the relationship between childhood abuse and HIV-related risk behavior. Child Abuse Negl 32:99-109 |
| Lejuez, C W; Bornovalova, Marina A; Reynolds, Elizabeth K et al. (2007) Risk factors in the relationship between gender and crack/cocaine. Exp Clin Psychopharmacol 15:165-75 |
| Bornovalova, Marina A; Daughters, Stacey B; Hernandez, Gustavo Daniel et al. (2005) Differences in impulsivity and risk-taking propensity between primary users of crack cocaine and primary users of heroin in a residential substance-use program. Exp Clin Psychopharmacol 13:311-8 |
