I am interested in the molecular biology, immunology, and the pathogenesis of the disease, Cryptococcosis, caused by C. neoformans. What is the relationship between the structure and the function in anticryptococcal antibodies? How does this relate to the development of a vaccine and for passive antibody therapy? These are some of the questions that fascinate me about this fungal organism.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
5F31GM018951-03
Application #
6138286
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Zlotnik, Hinda
Project Start
2000-01-01
Project End
Budget Start
2000-01-01
Budget End
2000-12-31
Support Year
3
Fiscal Year
2000
Total Cost
$35,850
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
009095365
City
Bronx
State
NY
Country
United States
Zip Code
10461
Rivera, Johanna; Mukherjee, Jean; Weiss, Louis M et al. (2002) Antibody efficacy in murine pulmonary Cryptococcus neoformans infection: a role for nitric oxide. J Immunol 168:3419-27
Feldmesser, M; Rivera, J; Kress, Y et al. (2000) Antibody interactions with the capsule of Cryptococcus neoformans. Infect Immun 68:3642-50