I am interested in the molecular biology, immunology, and the pathogenesis of the disease, Cryptococcosis, caused by C. neoformans. What is the relationship between the structure and the function in anticryptococcal antibodies? How does this relate to the development of a vaccine and for passive antibody therapy? These are some of the questions that fascinate me about this fungal organism.
Rivera, Johanna; Mukherjee, Jean; Weiss, Louis M et al. (2002) Antibody efficacy in murine pulmonary Cryptococcus neoformans infection: a role for nitric oxide. J Immunol 168:3419-27 |
Feldmesser, M; Rivera, J; Kress, Y et al. (2000) Antibody interactions with the capsule of Cryptococcus neoformans. Infect Immun 68:3642-50 |