The proposed development of significantly faster electron paramagnetic resonance imaging would enable measurement of fast decaying contrast agents. Images made using such contrast agents could be used in measuring changes in metabolic rates due to metabolic perturbations (e.g., tobacco smoking). The proposed method takes advantage of temporal redundancy to increase the rate at which individual images can be reconstructed.

Public Health Relevance

This project would develop significantly faster electron paramagnetic resonance imaging to enable measurement of fast decaying contrast agents. Images made using such contrast agents could be used in measuring changes in metabolic rates due to smoking or other metabolic perturbations.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
5F32EB012932-02
Application #
8265854
Study Section
Special Emphasis Panel (ZRG1-F15-D (20))
Program Officer
Erim, Zeynep
Project Start
2011-04-01
Project End
2013-07-31
Budget Start
2012-04-01
Budget End
2013-07-31
Support Year
2
Fiscal Year
2012
Total Cost
$55,184
Indirect Cost
Name
Ohio State University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
832127323
City
Columbus
State
OH
Country
United States
Zip Code
43210
Johnson, David H; Ahmad, Rizwan; Liu, Yangping et al. (2014) Uniform spinning sampling gradient electron paramagnetic resonance imaging. Magn Reson Med 71:893-900
Johnson, David H; Ahmad, Rizwan; He, Guanglong et al. (2014) Compressed sensing of spatial electron paramagnetic resonance imaging. Magn Reson Med 72:893-901
Chen, Zhiyu; Reyes, Levy A; Johnson, David H et al. (2013) Fast gated EPR imaging of the beating heart: spatiotemporally resolved 3D imaging of free-radical distribution during the cardiac cycle. Magn Reson Med 69:594-601
Palmer, J; Potter, L C; Johnson, D H et al. (2012) Dual-scan acquisition for accelerated continuous-wave EPR oximetry. J Magn Reson 222:53-8