Tobacco-related lung cancer is a leading cause of death among adults, and tobacco use accounts for -30% of cancer incidence and mortality. Therefore, eliminating tobacco uptake, increasing rates of tobacco cessation, and preventing smoking relapse are the cornerstones of cancer prevention. Moreover, a focus on groups disproportionately affected by tobacco use (e.g., minorities, low socioeconomic status (SES) groups, or populations at increased risk of relapse) is of clear importance in the fight against cancer. Previous research has shown that neighborhood-level SES is independently associated with higher smoking prevalence, but the role of the neighborhood in smoking outcome during a specific quit attempt has not been studied. The primary aim of this research is to examine how neighborhood characteristics influence the mechanisms underlying the process of smoking cessation and relapse prevention during a specific quit attempt among diverse community samples at increased risk for health disparities in cancer. Archival data will be examined from 4 study populations: Spanish speaking Hispanic smokers (n = 297), African-American smokers (n = 400), African-American, English speaking Hispanic, and Caucasian smokers in equal numbers (n = 420), and pregnant women who quit smoking and want to remain quit postpartum (n = 450).
Specific aims of this project are to: i) Evaluate the relation between neighborhood characteristics (including neighborhood-level SES, racial/ethnic composition, neighborhood problems, vigilance, social cohesion, and social control) and smoking abstinence; 2) Evaluate the relation of stress, depression, negative affect, self-efficacy, and social support with neighborhood characteristics and with smoking abstinence, respectively; and 3) Evaluate whether self-efficacy, depression, negative affect, stress, and/or social support mediate an observed association between neighborhood characteristics and abstinence. In a series of 4 studies, I will use multilevel modeling to examine the pathways through which the neighborhood context influences cessation using both questionnaire and ecological momentary assessment data, as well as sophisticated geographical software to map neighborhood-level demographic and economic data. These efforts will result in a better understanding of disparities in smoking status among underserved populations and provide information important for improving service to individuals from those communities, thereby affecting public health. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Center for Chronic Disease Prev and Health Promo (NCCDPHP)
Type
Research Scientist Development Award - Research & Training (K01)
Project #
1K01DP001120-01
Application #
7395190
Study Section
Special Emphasis Panel (ZCD1-ZDQ (05))
Program Officer
Irannejad, Nassi
Project Start
2007-08-31
Project End
2010-08-30
Budget Start
2007-08-31
Budget End
2008-08-30
Support Year
1
Fiscal Year
2007
Total Cost
$150,000
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Type
Schools of Medicine
DUNS #
800772139
City
Houston
State
TX
Country
United States
Zip Code
77030
Vidrine, Jennifer Irvin; Businelle, Michael S; Reitzel, Lorraine R et al. (2015) Coping Mediates the Association of Mindfulness with Psychological Stress, Affect, and Depression Among Smokers Preparing to Quit. Mindfulness (N Y) 6:433-443
Businelle, Michael S; Kendzor, Darla E; Reitzel, Lorraine R et al. (2013) Pathways linking socioeconomic status and postpartum smoking relapse. Ann Behav Med 45:180-91
Reitzel, Lorraine R; Kendzor, Darla E; Castro, Yessenia et al. (2013) The relation between social cohesion and smoking cessation among Black smokers, and the potential role of psychosocial mediators. Ann Behav Med 45:249-57
Kendzor, Darla E; Reitzel, Lorraine R; Mazas, Carlos A et al. (2012) Individual- and area-level unemployment influence smoking cessation among African Americans participating in a randomized clinical trial. Soc Sci Med 74:1394-401
Reitzel, Lorraine R; Vidrine, Jennifer I; Businelle, Michael S et al. (2012) Neighborhood perceptions are associated with tobacco dependence among African American smokers. Nicotine Tob Res 14:786-93
Castro, Yessenia; Costello, Tracy J; Correa-Fernández, Virmarie et al. (2011) Differential effects of depression on smoking cessation in a diverse sample of smokers in treatment. Am J Prev Med 41:84-7
Wetter, David W; McClure, Jennifer B; Cofta-Woerpel, Ludmila et al. (2011) A randomized clinical trial of a palmtop computer-delivered treatment for smoking relapse prevention among women. Psychol Addict Behav 25:365-71
Reitzel, Lorraine R; Businelle, Michael S; Kendzor, Darla E et al. (2011) Subjective social status predicts long-term smoking abstinence. BMC Public Health 11:135
Reitzel, Lorraine R; Vidrine, Jennifer Irvin; Businelle, Michael S et al. (2010) Preventing postpartum smoking relapse among diverse low-income women: a randomized clinical trial. Nicotine Tob Res 12:326-35
Reitzel, Lorraine R; Mazas, Carlos A; Cofta-Woerpel, Ludmila et al. (2010) Acculturative and neighborhood influences on subjective social status among Spanish-speaking Latino immigrant smokers. Soc Sci Med 70:677-83

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