This application is a competitive renewal for an Independent Scientist Award. The candidate, Tamara L. Wall, Ph.D., Associate Professor of Psychiatry at the University of California, San Diego, proposes to continue her program of research focused on factors and processes that predispose and/or protect individuals, particularly ethnic minorities, from alcohol and other substance involvement. The research plan includes six projects, three of which have been funded and are ongoing; the other three are being considered for funding or are under scientific review. The candidate's career goals are: (1) to advance her progress in becoming a leader in the scientific study of biological and psychosocial influences that lead to differences in alcohol involvement; (2) to increase her expertise in statistical modeling techniques, genetics, and related methodological issues; and (3) to continue to mentor junior scientists. The candidate has made a strong commitment to alcohol-related research. Activities for her continued career development include: (1) consultation with leading research scientists; (2) coursework in the analysis of longitudinal and genetically informative data, and the responsible conduct of research; and (3) participation in department seminars and scientific meetings. Renewal of Dr. Wall's Independent Scientist Award will provide her the opportunity to continue to engage in research activities on nearly a full-time basis, thus ensuring her continued development as a scientist and as a mentor.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Scientist Development Award - Research (K02)
Project #
5K02AA000269-10
Application #
7337992
Study Section
Special Emphasis Panel (ZAA1-FF (20))
Program Officer
Scott, Marcia S
Project Start
1998-08-01
Project End
2009-06-30
Budget Start
2008-01-01
Budget End
2009-06-30
Support Year
10
Fiscal Year
2008
Total Cost
$154,662
Indirect Cost
Name
University of California San Diego
Department
Psychiatry
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Luczak, Susan E; Liang, Tiebing; Wall, Tamara L (2017) Age of Drinking Initiation as a Risk Factor for Alcohol Use Disorder Symptoms is Moderated by ALDH2*2 and Ethnicity. Alcohol Clin Exp Res 41:1738-1744
Luczak, Susan E; Wall, Tamara L (2016) Gambling problems and comorbidity with alcohol use disorders in Chinese-, Korean-, and White-American college students. Am J Addict 25:195-202
Murray, Kate E; Klonoff, Elizabeth A; Garcini, Luz M et al. (2014) Assessing Acculturation Over Time: A Four-year Prospective Study of Asian American Young Adults. Asian Am J Psychol 5:252-261
Luczak, Susan E; Yarnell, Lisa M; Prescott, Carol A et al. (2014) Effects of ALDH2?2 on alcohol problem trajectories of Asian American college students. J Abnorm Psychol 123:130-40
Chartier, Karen G; Scott, Denise M; Wall, Tamara L et al. (2014) Framing ethnic variations in alcohol outcomes from biological pathways to neighborhood context. Alcohol Clin Exp Res 38:611-8
Otto, Jacqueline M; Hendershot, Christian S; Collins, Susan E et al. (2013) Association of the ALDH1A1*2 promoter polymorphism with alcohol phenotypes in young adults with or without ALDH2*2. Alcohol Clin Exp Res 37:164-9
Luczak, Susan E; Pandika, Danielle; Shea, Shoshana H et al. (2011) ALDH2 and ADH1B interactions in retrospective reports of low-dose reactions and initial sensitivity to alcohol in Asian American college students. Alcohol Clin Exp Res 35:1238-45
Hendershot, Christian S; Witkiewitz, Katie; George, William H et al. (2011) Evaluating a cognitive model of ALDH2 and drinking behavior. Alcohol Clin Exp Res 35:91-8
McCarthy, Denis M; Pedersen, Sarah L; Lobos, Elizabeth A et al. (2010) ADH1B*3 and response to alcohol in African-Americans. Alcohol Clin Exp Res 34:1274-81
Hendershot, Christian S; Otto, Jacqueline M; Collins, Susan E et al. (2010) Evaluation of a brief web-based genetic feedback intervention for reducing alcohol-related health risks associated with ALDH2. Ann Behav Med 40:77-88

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