An Independent Scientist Award (K02) is requested to allow the candidate to continue to focus on and to expand his research programs on the impact of aftercare for substance abusers and the assessment of factors in relapse. The award would also make it possible for the candidate to pursue additional training in longitudinal data analytic techniques, cost-effective research, and assessment instrument development. These training experiences will be accomplished through a combination of formal course work and directed readings with acknowledged experts in these areas. The candidate's long-term career goal is to integrate findings from studies of various approaches to continuing care, or """"""""aftercare,"""""""" and studies of factors in relapse to generate more effective and cost-effective approaches to relapse prevention in substance abusers. As described in the research plan, during the term of support from this proposed Independent Scientist Award the candidate will serve as Principal Investigator on two RO1 grants that evaluate the effectiveness and cost-effectiveness of aftercare of cocaine and alcohol dependent individuals who have completed a primary treatment program. As these projects are similar, only the cocaine study is described in detail. In this project, entitled """"""""Aftercare for Cocaine Patients: Effectiveness and Costs,"""""""" cocaine dependent patients who complete intensive outpatient rehabilitation (IOP) will be randomly assigned to one of the following interventions: (1) Minimal aftercare (MIN), a combination of referral to self-help groups and brief telephone case-management; (2) Standard disease model aftercare counseling (STND), provided through two group therapy sessions per week; and (3) Individual aftercare (IND), provided through one individual cognitive-behavioral, relapse prevention session and one group therapy session per week. The effectiveness analysis will include the testing of main effect and patient by treatment """"""""matching"""""""" hypotheses generated by prior work by the candidate and other investigators. The cost-effectiveness analysis, which will be done in collaboration with Dr. Donald Shepard of Brandeis University, will focus on the identification of the types of patients who are treated most cost effectively in each aftercare condition. Based on prior research, it is anticipated that the IND condition will be particularly effective, relative to the other conditions, for poor prognosis patients, such as those who did not achieve remission from cocaine dependence during IOP and those with greater psychiatric severity. Outcome measures in this study will include measures of cocaine and alcohol use and frequency of behaviors that place patients at high risk for contracting or spreading AIDS. The funding provided by the KO2 award also will allow the candidate to further the development and refinement of the Cocaine Relapse Interview, an assessment instrument that was initially developed with a First Award.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Scientist Development Award - Research (K02)
Project #
5K02DA000361-02
Application #
2897648
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Czechowicz, Dorynne D
Project Start
1998-04-01
Project End
2003-03-31
Budget Start
1999-04-01
Budget End
2000-03-31
Support Year
2
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Psychiatry
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Wimberly, Alexandra S; Hyatt, Jordan M; McKay, James R (2018) Effect of continuing care for people with cocaine dependence on criminal justice sentences. Behav Sci Law 36:116-129
Wimberly, Alexandra S; Ivey, Megan; Rennert, Lior et al. (2017) Effect of Continuing Care for Cocaine Dependence on HIV Sex-Risk Behaviors. AIDS Behav 21:1082-1090
Shepard, Donald S; Daley, Marilyn C; Neuman, Matthew J et al. (2016) Telephone-based continuing care counseling in substance abuse treatment: Economic analysis of a randomized trial. Drug Alcohol Depend 159:109-16
Foulds, Jonathan; Veldheer, Susan; Yingst, Jessica et al. (2015) Development of a questionnaire for assessing dependence on electronic cigarettes among a large sample of ex-smoking E-cigarette users. Nicotine Tob Res 17:186-92
McKay, James R; Van Horn, Deborah H A; Lynch, Kevin G et al. (2014) Who benefits from extended continuing care for cocaine dependence? Addict Behav 39:660-8
McKay, James R; Van Horn, Deborah H A; Lynch, Kevin G et al. (2013) An adaptive approach for identifying cocaine dependent patients who benefit from extended continuing care. J Consult Clin Psychol 81:1063-73
McKay, James R; Van Horn, Deborah; Oslin, David W et al. (2011) Extended telephone-based continuing care for alcohol dependence: 24-month outcomes and subgroup analyses. Addiction 106:1760-9
McKay, James R; Hiller-Sturmhofel, Susanne (2011) Treating alcoholism as a chronic disease: approaches to long-term continuing care. Alcohol Res Health 33:356-70
Lynch, Kevin G; Van Horn, Deborah; Drapkin, Michelle et al. (2010) Moderators of response to telephone continuing care for alcoholism. Am J Health Behav 34:788-800
McKay, James R; Lynch, Kevin G; Coviello, Donna et al. (2010) Randomized trial of continuing care enhancements for cocaine-dependent patients following initial engagement. J Consult Clin Psychol 78:111-20

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