? A second five-year Independent Scientist Award (K02) is requested to allow the candidate to continue to focus on and to expand his research programs on developing enhanced treatments to improve the outcomes of substance abuse patients. The award would also make it possible for the candidate to pursue further training in newer longitudinal data analytic techniques, economic research (i.e., benefit-cost, cost-effectiveness), and adaptive (i.e., flexible) treatment interventions that can be modified in response to change in patient symptoms or status over time. The proposed training will be accomplished through collaborations and guided readings with experts in these areas. ? ? During the funding period, the candidate will complete two continuing care studies for which he is the PI, and the primary manuscripts describing results from these studies. Initial results support the use of adaptive, telephone-based continuing care interventions with alcohol and cocaine dependent patients. In addition, the candidate is the PI of another NIDA-funded R01 (in year 2 of 5) that compares three enhanced treatment approaches for cocaine-dependent patients participating in an Intensive Outpatient program (lOP) to treatment as usual in lOP. Recent studies have indicated that the addition of services for concurrent psychiatric, interpersonal, and employment problems can improve substance use outcomes for patients, particularly if they have greater problem severity in these areas. An independent line of research has generated considerable evidence that providing reinforcement in the form of vouchers, contingent on providing drug-free urine samples, that can be redeemed for goods and services can also lead to improved substance use outcomes. These findings suggest that there may be two conceptually and theoretically different, behaviorally-based avenues for improving treatment outcomes for substance abusers. The candidate's current study uses a 2 x 2 design to investigate the main effects and potential interaction effects of services matched to problems and voucher reinforcement of abstinence. The cost-effectiveness and benefit cost of each of the enhanced interventions will also be determined, through a collaboration with Dr. Michael French. ? ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Scientist Development Award - Research (K02)
Project #
5K02DA000361-10
Application #
7415196
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Mcnamara-Spitznas, Cecilia M
Project Start
1998-04-01
Project End
2010-04-30
Budget Start
2008-05-01
Budget End
2010-04-30
Support Year
10
Fiscal Year
2008
Total Cost
$129,413
Indirect Cost
Name
University of Pennsylvania
Department
Psychiatry
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Wimberly, Alexandra S; Hyatt, Jordan M; McKay, James R (2018) Effect of continuing care for people with cocaine dependence on criminal justice sentences. Behav Sci Law 36:116-129
Wimberly, Alexandra S; Ivey, Megan; Rennert, Lior et al. (2017) Effect of Continuing Care for Cocaine Dependence on HIV Sex-Risk Behaviors. AIDS Behav 21:1082-1090
Shepard, Donald S; Daley, Marilyn C; Neuman, Matthew J et al. (2016) Telephone-based continuing care counseling in substance abuse treatment: Economic analysis of a randomized trial. Drug Alcohol Depend 159:109-16
Foulds, Jonathan; Veldheer, Susan; Yingst, Jessica et al. (2015) Development of a questionnaire for assessing dependence on electronic cigarettes among a large sample of ex-smoking E-cigarette users. Nicotine Tob Res 17:186-92
McKay, James R; Van Horn, Deborah H A; Lynch, Kevin G et al. (2014) Who benefits from extended continuing care for cocaine dependence? Addict Behav 39:660-8
McKay, James R; Van Horn, Deborah H A; Lynch, Kevin G et al. (2013) An adaptive approach for identifying cocaine dependent patients who benefit from extended continuing care. J Consult Clin Psychol 81:1063-73
McKay, James R; Van Horn, Deborah; Oslin, David W et al. (2011) Extended telephone-based continuing care for alcohol dependence: 24-month outcomes and subgroup analyses. Addiction 106:1760-9
McKay, James R; Hiller-Sturmhofel, Susanne (2011) Treating alcoholism as a chronic disease: approaches to long-term continuing care. Alcohol Res Health 33:356-70
Lynch, Kevin G; Van Horn, Deborah; Drapkin, Michelle et al. (2010) Moderators of response to telephone continuing care for alcoholism. Am J Health Behav 34:788-800
McKay, James R; Lynch, Kevin G; Coviello, Donna et al. (2010) Randomized trial of continuing care enhancements for cocaine-dependent patients following initial engagement. J Consult Clin Psychol 78:111-20

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