Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Modified Research Career Development Award (K04)
Project #
7K04AI000882-03
Application #
3070933
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1990-01-01
Project End
1993-08-31
Budget Start
1990-01-01
Budget End
1990-08-31
Support Year
3
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Wayne State University
Department
Type
Schools of Medicine
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Bokhari, Abdullah A B; Solomon, Tsione; Desai, Sanjay A (2008) Two distinct mechanisms of transport through the plasmodial surface anion channel. J Membr Biol 226:27-34
Staines, Henry M; Alkhalil, Abdulnaser; Allen, Richard J et al. (2007) Electrophysiological studies of malaria parasite-infected erythrocytes: current status. Int J Parasitol 37:475-82
Alkhalil, Abdulnaser; Hill, David A; Desai, Sanjay A (2007) Babesia and plasmodia increase host erythrocyte permeability through distinct mechanisms. Cell Microbiol 9:851-60
Lisk, Godfrey; Scott, Seth; Solomon, Tsione et al. (2007) Solute-inhibitor interactions in the plasmodial surface anion channel reveal complexities in the transport process. Mol Pharmacol 71:1241-50
Lisk, Godfrey; Kang, Myungsa; Cohn, Jamieson V et al. (2006) Specific inhibition of the plasmodial surface anion channel by dantrolene. Eukaryot Cell 5:1882-93
Lisk, Godfrey; Desai, Sanjay A (2006) Improved perfusion conditions for patch-clamp recordings on human erythrocytes. Biochem Biophys Res Commun 347:158-65
Desai, Sanjay A (2005) Open and closed states of the plasmodial surface anion channel. Nanomedicine 1:58-66
Kang, Myungsa; Lisk, Godfrey; Hollingworth, Stephen et al. (2005) Malaria parasites are rapidly killed by dantrolene derivatives specific for the plasmodial surface anion channel. Mol Pharmacol 68:34-40
Desai, Sanjay A; Alkhalil, Abdulnaser; Kang, Myungsa et al. (2005) Plasmodial surface anion channel-independent phloridzin resistance in Plasmodium falciparum. J Biol Chem 280:16861-7
Lisk, Godfrey; Desai, Sanjay A (2005) The plasmodial surface anion channel is functionally conserved in divergent malaria parasites. Eukaryot Cell 4:2153-9

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