Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08DK002281-03
Application #
2134153
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1994-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Orloff, Mohammed S; Iyengar, Sudha K; Winkler, Cheryl A et al. (2005) Variants in the Wilms' tumor gene are associated with focal segmental glomerulosclerosis in the African American population. Physiol Genomics 21:212-21
Iyengar, Sudha K; Fox, Katherine A; Schachere, Marlene et al. (2003) Linkage analysis of candidate loci for end-stage renal disease due to diabetic nephropathy. J Am Soc Nephrol 14:S195-201
Iyengar, Sudha K; Schelling, Jeffrey R; Sedor, John R (2002) Approaches to understanding susceptibility to nephropathy: from genetics to genomics. Kidney Int 61:S61-7
Khan, S; Koepke, A; Jarad, G et al. (2001) Apoptosis and JNK activation are differentially regulated by Fas expression level in renal tubular epithelial cells. Kidney Int 60:65-76
Schelling, J R (2000) Fatal hypermagnesemia. Clin Nephrol 53:61-5
El-Meanawy, M A; Schelling, J R; Pozuelo, F et al. (2000) Use of serial analysis of gene expression to generate kidney expression libraries. Am J Physiol Renal Physiol 279:F383-92
Singh, R; Wang, B; Shirvaikar, A et al. (1999) The IL-1 receptor and Rho directly associate to drive cell activation in inflammation. J Clin Invest 103:1561-70
Huang, S; Konieczkowski, M; Schelling, J R et al. (1999) Interleukin-1 stimulates Jun N-terminal/stress-activated protein kinase by an arachidonate-dependent mechanism in mesangial cells. Kidney Int 55:1740-9
Schelling, J R; Zarif, L; Sehgal, A et al. (1999) Genetic susceptibility to end-stage renal disease. Curr Opin Nephrol Hypertens 8:465-72
Schelling, J R; Cleveland, R P (1999) Involvement of Fas-dependent apoptosis in renal tubular epithelial cell deletion in chronic renal failure. Kidney Int 56:1313-6

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