Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08HL002595-05
Application #
2210238
Study Section
Special Emphasis Panel (SRC (JQ))
Project Start
1991-05-01
Project End
1995-08-30
Budget Start
1995-05-01
Budget End
1995-08-30
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Pediatrics
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Koliwad, S K; Kunze, D L; Elliott, S J (1996) Oxidant stress activates a non-selective cation channel responsible for membrane depolarization in calf vascular endothelial cells. J Physiol 491 ( Pt 1):1-12
Koliwad, S K; Elliott, S J; Kunze, D L (1996) Oxidized glutathione mediates cation channel activation in calf vascular endothelial cells during oxidant stress. J Physiol 495 ( Pt 1):37-49
Elliott, S J (1996) Peroxynitrite modulates receptor-activated Ca2+ signaling in vascular endothelial cells. Am J Physiol 270:L954-61
Wesson, D E; Elliott, S J (1995) The H2O2-generating enzyme, xanthine oxidase, decreases luminal Ca2+ content of the IP3-sensitive Ca2+ store in vascular endothelial cells. Microcirculation 2:195-203
Elliott, S J; Doan, T N; Henschke, P N (1995) Reductant substrate for glutathione peroxidase modulates oxidant inhibition of Ca2+ signaling in endothelial cells. Am J Physiol 268:H278-87
Henschke, P N; Elliott, S J (1995) Oxidized glutathione decreases luminal Ca2+ content of the endothelial cell ins(1,4,5)P3-sensitive Ca2+ store. Biochem J 312 ( Pt 2):485-9
Elliott, S J; Koliwad, S K (1995) Oxidant stress and endothelial membrane transport. Free Radic Biol Med 19:649-58
Doan, T N; Gentry, D L; Taylor, A A et al. (1994) Hydrogen peroxide activates agonist-sensitive Ca(2+)-flux pathways in canine venous endothelial cells. Biochem J 297 ( Pt 1):209-15
Elliott, S J; Doan, T N (1993) Oxidant stress inhibits the store-dependent Ca(2+)-influx pathway of vascular endothelial cells. Biochem J 292 ( Pt 2):385-93
Elliott, S J; Doan, T N; Schilling, W P (1993) Role of lipid peroxidation in tert-butylhydroperoxide-induced inhibition of endothelial cell calcium signaling. J Pharmacol Exp Ther 264:1063-70

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