Over the past decade there has been considerable progress in recognition of the wide scope and complexity of women's health issues. It is now recognized that the health needs of women extend far beyond their reproductive system and include a wide range of conditions that are unique to women, more prevalent or serious in women, and/or inadequately addressed in women. A recent Institute of Medicine report found that sex is an important basic human variable that should be considered in designing and analyzing studies in all areas of basic and clinical research, that every cell has a sex, and that a person's genetic sex affects behavior and affects health. Research in women's health derives directly from understanding sex differences in biology and medicine. Herein, we propose a mentored, interdisciplinary program of advanced training and career development for physicians and scientists in women's health research and sex-based biology. We draw from the strengths of programs and faculty mentors/researchers at Stanford University from the disciplines of endocrinology, genetics, oncology, genomics, information technology, tissue engineering, pharmacology, psychiatry, medicine, pediatrics, OB/GYN, epidemiology, health policy, disease prevention, and biostatistics. The theme of the Interdisciplinary Women's Health Research (IWHR) Career Development Program at Stanford University is advanced, rigorous mentoring in women's health research from bench to bedside. The program will provide IWHR Scholars with structured, interdisciplinary research and didactic experiences, concomitantly with mentoring by experienced researchers and physician scientists. It will accommodate trainees with varying levels of experience in women's health research and derives from a broad based initiative with research, mentoring, and trainee evaluation as cornerstones of the program. The goal of the IWHR Career Development Center is to bridge the time period between clinical or research training with independent research careers and to foster the development of future leaders in women's health research in the United States.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12HD043452-04
Application #
6949941
Study Section
Special Emphasis Panel (ZRG1-MDCN-2 (05))
Program Officer
Lamar, Charisee A
Project Start
2002-09-27
Project End
2007-07-31
Budget Start
2005-08-01
Budget End
2006-07-31
Support Year
4
Fiscal Year
2005
Total Cost
$500,000
Indirect Cost
Name
Stanford University
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
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Carvalho, Brendan; Clark, David J; Yeomans, David et al. (2012) Collecting and measuring wound exudate biochemical mediators in surgical wounds. J Vis Exp :
Carvalho, Brendan; Clark, David J; Yeomans, David C et al. (2010) Continuous subcutaneous instillation of bupivacaine compared to saline reduces interleukin 10 and increases substance P in surgical wounds after cesarean delivery. Anesth Analg 111:1452-9
Kurian, Allison W; Gong, Gail D; Chun, Nicolette M et al. (2008) Performance of BRCA1/2 mutation prediction models in Asian Americans. J Clin Oncol 26:4752-8
Backes, Andrea C; Abbasi, Fahim; Lamendola, Cindy et al. (2008) Clinical experience with a relatively low carbohydrate, calorie-restricted diet improves insulin sensitivity and associated metabolic abnormalities in overweight, insulin resistant South Asian Indian women. Asia Pac J Clin Nutr 17:669-71
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Carvalho, Brendan; Clark, David J; Yeomans, David et al. (2008) Collecting and measuring nociceptive and inflammatory mediators in surgical wounds. J Vis Exp :
Carvalho, Brendan; Clark, David J; Angst, Martin S (2008) Local and systemic release of cytokines, nerve growth factor, prostaglandin E2, and substance P in incisional wounds and serum following cesarean delivery. J Pain 9:650-7
Martin, Marlene; Palaniappan, Latha P; Kwan, Andrea C et al. (2008) Ethnic differences in the relationship between adiponectin and insulin sensitivity in South Asian and Caucasian women. Diabetes Care 31:798-801
Carvalho, Brendan; Roland, Laura M; Chu, Larry F et al. (2007) Single-dose, extended-release epidural morphine (DepoDur) compared to conventional epidural morphine for post-cesarean pain. Anesth Analg 105:176-83

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