This is a request for a Mentored Patient-Oriented Career Development Award. Over the five years of the award, the candidate will conduct one observational study and two clinical trials of hospital-based interventions to improve drug abuse treatment entry and retention among medicine inpatients. Primary mentorship will be provided by Drs. George Bigelow and Daniel Ford. Additional mentoring and tutorial assistance will be provide by Drs. Maxine Stitzer, Laura Morlock, and Carlo DiClemente. The goals for this career development project are to better understand the role of the medical hospitalization on motivation for treatment and readiness for change and to assess whether clinical interventions can improve subsequent treatment entry and retention.
Specific aims are to (1) identify factors within an acute hospitalization episode that influence a person's motivation for and actual entry into treatment. (2) Determine whether hospital-based clinical interventions improve treatment entry and retention upon hospital discharge. (3) Determine whether these interventions effect subsequent health utilization and management of concurrent HIV infection. Three sub-studies will be conducted on a cohort of substance abusing patients admitted to the medicine service at Johns Hopkins Hospital: (a) an observational, longitudinal study of substance abusing medicine inpatients; (2) a randomized clinical trials of peer mentor-structured transitional support and (3) a quasi-experimental study of concurrently administered substance abuse treatment. This program of research and training will provide important information on the acute medical hospitalization for substance abusing patients and how it can best be structured to improve health care and substance abuse outcomes.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Mentored Patient-Oriented Research Career Development Award (K23)
Project #
7K23DA013988-04
Application #
6800549
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Czechowicz, Dorynne D
Project Start
2001-09-30
Project End
2006-08-31
Budget Start
2004-09-01
Budget End
2005-08-31
Support Year
4
Fiscal Year
2004
Total Cost
$131,490
Indirect Cost
Name
Georgetown University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
O'Toole, Thomas P; Pollini, Robin A; Ford, Daniel E et al. (2008) The health encounter as a treatable moment for homeless substance-using adults: the role of homelessness, health seeking behavior, readiness for behavior change and motivation for treatment. Addict Behav 33:1239-43
O'Toole, Thomas P; Pollini, Robin A; Ford, Daniel E et al. (2007) The effect of integrated medical-substance abuse treatment during an acute illness on subsequent health services utilization. Med Care 45:1110-5
O'Toole, Thomas P; Pollini, Robin; Gray, Paulette et al. (2007) Factors identifying high-frequency and low-frequency health service utilization among substance-using adults. J Subst Abuse Treat 33:51-9
O'Toole, Thomas P; Conde-Martel, Alicia; Gibbon, Jeanette L et al. (2007) Where do people go when they first become homeless? A survey of homeless adults in the USA. Health Soc Care Community 15:446-53
O'Toole, Thomas P; Conde-Martel, Alicia; Young, J Hunter et al. (2006) Managing acutely ill substance-abusing patients in an integrated day hospital outpatient program: medical therapies, complications, and overall treatment outcomes. J Gen Intern Med 21:570-6
Pollini, Robin A; O'Toole, Thomas P; Ford, Daniel et al. (2006) Does this patient really want treatment? Factors associated with baseline and evolving readiness for change among hospitalized substance using adults interested in treatment. Addict Behav 31:1904-18
Garibaldi, Brian; Conde-Martel, Alicia; O'Toole, Thomas P (2005) Self-reported comorbidities, perceived needs, and sources for usual care for older and younger homeless adults. J Gen Intern Med 20:726-30
O'Toole, Thomas P; Gibbon, Jeanette L; Hanusa, Barbara H et al. (2004) Self-reported changes in drug and alcohol use after becoming homeless. Am J Public Health 94:830-5
O'Toole, Thomas P; Conde-Martel, Alicia; Gibbon, Jeanette L et al. (2003) Health care of homeless veterans. J Gen Intern Med 18:929-33
O'Toole, Thomas P; Strain, Eric C; Wand, Gary et al. (2002) Outpatient treatment entry and health care utilization after a combined medical/substance abuse intervention for hospitalized medical patients. J Gen Intern Med 17:334-40