K. Davidson is a licensed clinical psychologist with previous training in empirically supported/validated psychological therapies. She has previous experience in conducting psychological interventions, but she has limited training and research experience with medical patient populations. Her long-term goal is to propose, test, and empirically validate psychological therapy protocols with hypertensive patients. This award will aid by providing the time and resources for K. Davidson to acquire knowledge and expertise in the following eight modules: 1) hypertension pathophysiology; 2) hypertensionpharmacology; 3) Medical Ethics; 4) hypertension epidemiology and risk factor analyses; 5) ambulatory and continuous blood pressure monitoring technology; 6) randomized controlled trial statistical and design issues; and, 7) research dissemination and grant submission for randomized controlled psychological interventions with hypertension patients. Mount Sinai School of Medicine is an ideal environment for this training experience as it has commissioned a new Integrative & Behavioral Cardiology program to provide empirically based psychological and complimentary interventions to its patients, and already has an existing Hypertension section. Dr. Pickering is an ideal mentor because of his world-renowned hypertension expertise. The major aim of the current project is to test the feasibility of comparing an anger management group plus usual medical care to two control conditions-usual medical care only and another group therapy (time management) plus usual medical care. Thus, aims are to obtain patient retention and effectiveness estimates of eligible volunteering hypertension patients with anger problems, who complete the intervention prototocol. The design will be a randomized, blood pressure, medication, and anger expression- matched, two control arm design, with 20 medicated, uncontrolled hypertension patients in each condition. Objectives include collecting estimates to propose a large-scale clinical trial, and offering a standardized, evidence-based treatment to medicated uncontrolled hypertension patients who additionally have anger expression difficulties so that better blood pressure control can be obtained.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Mentored Patient-Oriented Research Career Development Award (K23)
Project #
5K23HL004458-04
Application #
6800332
Study Section
Special Emphasis Panel (ZHL1-CSR-F (M1))
Program Officer
Czajkowski, Susan
Project Start
2001-09-04
Project End
2006-08-31
Budget Start
2004-09-01
Budget End
2005-08-31
Support Year
4
Fiscal Year
2004
Total Cost
$129,222
Indirect Cost
Name
Columbia University (N.Y.)
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032
Rom Korin, Maya; Chaplin, William F; Shaffer, Jonathan A et al. (2013) Men's and women's health beliefs differentially predict coronary heart disease incidence in a population-based sample. Health Educ Behav 40:231-9
Denton, Ellen-Ge D; Rieckmann, Nina; Davidson, Karina W et al. (2012) Psychosocial vulnerabilities to depression after acute coronary syndrome: the pivotal role of rumination in predicting and maintaining depression. Front Psychol 3:288
Ishikawa, Joji; Nasothimiou, Efthimia G; Karpettas, Nikos et al. (2012) Automatic office blood pressure measured without doctors or nurses present. Blood Press Monit 17:96-102
Kronish, Ian M; Woodward, Mark; Sergie, Ziad et al. (2011) Meta-analysis: impact of drug class on adherence to antihypertensives. Circulation 123:1611-21
Davidson, Karina W; Mostofsky, Elizabeth; Whang, William (2010) Don't worry, be happy: positive affect and reduced 10-year incident coronary heart disease: the Canadian Nova Scotia Health Survey. Eur Heart J 31:1065-70
Davidson, Karina W; Burg, Matthew M; Kronish, Ian M et al. (2010) Association of anhedonia with recurrent major adverse cardiac events and mortality 1 year after acute coronary syndrome. Arch Gen Psychiatry 67:480-8
Davidson, Karina W; Schwartz, Joseph E; Kirkland, Susan A et al. (2009) Relation of inflammation to depression and incident coronary heart disease (from the Canadian Nova Scotia Health Survey [NSHS95] Prospective Population Study). Am J Cardiol 103:755-61
Burg, Matthew M; Lesperance, Francois; Rieckmann, Nina et al. (2008) Treating persistent depressive symptoms in post-ACS patients: the project COPES phase-I randomized controlled trial. Contemp Clin Trials 29:231-40
Goodman, Jeanne; Shimbo, Daichi; Haas, Donald C et al. (2008) Incident and recurrent major depressive disorder and coronary artery disease severity in acute coronary syndrome patients. J Psychiatr Res 42:670-5
Rieckmann, Nina; Burg, Matthew M; Gerin, William et al. (2006) Depression vulnerabilities in patients with different levels of depressive symptoms after acute coronary syndromes. Psychother Psychosom 75:353-61

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