The proposed K23 application will strongly support Dr. Raeanne Moore's long-term career goal of becoming an independent clinical scientist investigating and promoting optimal functioning among older HIV+ adults, with applied expertise in using innovative mobile health technologies. The proposal has considerable

Public Health Relevance

Daily functioning difficulties are common among older persons living with HIV, and disability costs associated with these impairments place a significant burden on society. Available assessment methods do not capture the combination of risk and protective factors impacting daily functioning at the intersection of HIV and aging, and the proposed study will use Ecological Momentary Assessment (EMA) as a low cost, efficient, objective measure of functioning among older persons with HIV. Understanding the primary factors leading to functional impairments at an individual level will inform the development of new interventions aimed at reducing disability and improving overall quality of life among older persons living with HIV.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Mentored Patient-Oriented Research Career Development Award (K23)
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Study Section
Behavioral and Social Consequences of HIV/AIDS Study Section (BSCH)
Program Officer
Brouwers, Pim
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University of California, San Diego
Schools of Medicine
La Jolla
United States
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Oppenheim, Hannah; Paolillo, Emily W; Moore, Raeanne C et al. (2018) Neurocognitive functioning predicts frailty index in HIV. Neurology 91:e162-e170
Paolillo, Emily W; Tang, Bin; Depp, Colin A et al. (2018) Temporal Associations Between Social Activity and Mood, Fatigue, and Pain in Older Adults With HIV: An Ecological Momentary Assessment Study. JMIR Ment Health 5:e38
Moore, Raeanne C; Hussain, Mariam A; Watson, Caitlin W-M et al. (2018) Grit and Ambition are Associated with Better Neurocognitive and Everyday Functioning Among Adults Living with HIV. AIDS Behav 22:3214-3225
Sundermann, Erin E; Heaton, Robert K; Pasipanodya, Elizabeth et al. (2018) Sex differences in HIV-associated cognitive impairment: an observational cohort study. AIDS :
Paolillo, Emily W; Obermeit, Lisa C; Tang, Bin et al. (2018) Smartphone-based ecological momentary assessment (EMA) of alcohol and cannabis use in older adults with and without HIV infection. Addict Behav 83:102-108
Moore, David J; Fazeli, Pariya L; Moore, Raeanne C et al. (2018) Positive Psychological Factors are Linked to Successful Cognitive Aging Among Older Persons Living with HIV/AIDS. AIDS Behav 22:1551-1561
Moore, Raeanne C; Swendsen, Joel; Depp, Colin A (2017) Applications for self-administered mobile cognitive assessments in clinical research: A systematic review. Int J Methods Psychiatr Res 26:
Moore, Raeanne C; Paolillo, Emily W; Heaton, Anne et al. (2017) Clinical utility of the UCSD Performance-Based Skills Assessment-Brief (UPSA-B) in adults living with HIV: Associations with neuropsychological impairment and patient-reported everyday functioning difficulties. PLoS One 12:e0183614
Kaufmann, Christopher N; Orff, Henry J; Moore, Raeanne C et al. (2017) Psychometric Characteristics of the Insomnia Severity Index in Veterans With History of Traumatic Brain Injury. Behav Sleep Med :1-9
Fazeli, P L; Casaletto, K B; Paolillo, E et al. (2017) Screening for neurocognitive impairment in HIV-positive adults aged 50 years and older: Montreal Cognitive Assessment relates to self-reported and clinician-rated everyday functioning. J Clin Exp Neuropsychol 39:842-853

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