Operation of A Molecular Virology/Immunology Laboratory

Gerin, John L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research and Development Contracts (N01)
• Project #: N01AI045179-000
• Application #: 2296003
• Project Start: 1993-10-16
• Project End: 1998-10-15
• Budget Start: 1993-10-16
• Budget End: 1994-10-15
• Fiscal Year: 1994

Institution

• Name: Georgetown University
• Department: Microbiology/Immun/Virology
• Type: Schools of Dentistry
• DUNS #: 049515844
• City: Washington
• State: DC
• Country: United States
• Zip Code: 20057

Publications

Choo, Hyunah; Beadle, James R; Kern, Earl R et al. (2007) Antiviral activities of novel 5-phosphono-pent-2-en-1-yl nucleosides and their alkoxyalkyl phosphonoesters. Antimicrob Agents Chemother 51:611-5

Painter, George R; Almond, Merrick R; Trost, Lawrence C et al. (2007) Evaluation of hexadecyloxypropyl-9-R-[2-(Phosphonomethoxy)propyl]- adenine, CMX157, as a potential treatment for human immunodeficiency virus type 1 and hepatitis B virus infections. Antimicrob Agents Chemother 51:3505-9

Casey, John L; Tennant, Bud C; Gerin, John L (2006) Genetic changes in hepatitis delta virus from acutely and chronically infected woodchucks. J Virol 80:6469-77

Casey, John; Cote, Paul J; Toshkov, Illia A et al. (2005) Clevudine inhibits hepatitis delta virus viremia: a pilot study of chronically infected woodchucks. Antimicrob Agents Chemother 49:4396-9

Korba, Brent E; Cote, Paul J; Menne, Stephan et al. (2004) Clevudine therapy with vaccine inhibits progression of chronic hepatitis and delays onset of hepatocellular carcinoma in chronic woodchuck hepatitis virus infection. Antivir Ther 9:937-52

Wang, Y; Jacob, J R; Menne, S et al. (2004) Interferon-gamma-associated responses to woodchuck hepatitis virus infection in neonatal woodchucks and virus-infected hepatocytes. J Viral Hepat 11:404-17

Menne, Stephan; Cote, Paul J (2004) Measurement of cell-mediated immune response in woodchucks. Methods Mol Med 96:27-36

Wang, Yun; Menne, Stephan; Jacob, James R et al. (2003) Role of type 1 versus type 2 immune responses in liver during the onset of chronic woodchuck hepatitis virus infection. Hepatology 37:771-80

Menne, Stephan; Roneker, Carol A; Tennant, Bud C et al. (2002) Immunogenic effects of woodchuck hepatitis virus surface antigen vaccine in combination with antiviral therapy: breaking of humoral and cellular immune tolerance in chronic woodchuck hepatitis virus infection. Intervirology 45:237-50

Tatti, Kathleen M; Korba, Brent E; Stang, Heather L et al. (2002) Mutations in the conserved woodchuck hepatitis virus polymerase FLLA and YMDD regions conferring resistance to lamivudine. Antiviral Res 55:141-50