Project Start
1993-10-16
Project End
1998-10-15
Budget Start
1997-09-18
Budget End
1998-10-15
Support Year
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Georgetown University
Department
Microbiology/Immun/Virology
Type
Schools of Dentistry
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Choo, Hyunah; Beadle, James R; Kern, Earl R et al. (2007) Antiviral activities of novel 5-phosphono-pent-2-en-1-yl nucleosides and their alkoxyalkyl phosphonoesters. Antimicrob Agents Chemother 51:611-5
Painter, George R; Almond, Merrick R; Trost, Lawrence C et al. (2007) Evaluation of hexadecyloxypropyl-9-R-[2-(Phosphonomethoxy)propyl]- adenine, CMX157, as a potential treatment for human immunodeficiency virus type 1 and hepatitis B virus infections. Antimicrob Agents Chemother 51:3505-9
Casey, John L; Tennant, Bud C; Gerin, John L (2006) Genetic changes in hepatitis delta virus from acutely and chronically infected woodchucks. J Virol 80:6469-77
Casey, John; Cote, Paul J; Toshkov, Illia A et al. (2005) Clevudine inhibits hepatitis delta virus viremia: a pilot study of chronically infected woodchucks. Antimicrob Agents Chemother 49:4396-9
Korba, Brent E; Cote, Paul J; Menne, Stephan et al. (2004) Clevudine therapy with vaccine inhibits progression of chronic hepatitis and delays onset of hepatocellular carcinoma in chronic woodchuck hepatitis virus infection. Antivir Ther 9:937-52
Wang, Y; Jacob, J R; Menne, S et al. (2004) Interferon-gamma-associated responses to woodchuck hepatitis virus infection in neonatal woodchucks and virus-infected hepatocytes. J Viral Hepat 11:404-17
Menne, Stephan; Cote, Paul J (2004) Measurement of cell-mediated immune response in woodchucks. Methods Mol Med 96:27-36
Wang, Yun; Menne, Stephan; Jacob, James R et al. (2003) Role of type 1 versus type 2 immune responses in liver during the onset of chronic woodchuck hepatitis virus infection. Hepatology 37:771-80
Menne, Stephan; Roneker, Carol A; Roggendorf, Michael et al. (2002) Deficiencies in the acute-phase cell-mediated immune response to viral antigens are associated with development of chronic woodchuck hepatitis virus infection following neonatal inoculation. J Virol 76:1769-80
Menne, Stephan; Roneker, Carol A; Korba, Brent E et al. (2002) Immunization with surface antigen vaccine alone and after treatment with 1-(2-fluoro-5-methyl-beta-L-arabinofuranosyl)-uracil (L-FMAU) breaks humoral and cell-mediated immune tolerance in chronic woodchuck hepatitis virus infection. J Virol 76:5305-14

Showing the most recent 10 out of 32 publications