The specific objectives of this contract are: 1) to define the acute toxicities of new anticancer agents with advanced cancer; 2) to redefine the acute toxicities and pharmacokinetics of anticancer administered in combination with agents to modulate toxicity or antitumor effect; 3) to provide information on the pharmacokinetic characteristics (absorption, distribution, metabolism and elimination) and pharmacodynamics of selected antitumor agents; 4) to determine a treatment regimen suitable for evaluation of antitumor activity in Phase II trials.

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Treatment (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CM007302-004
Application #
3607834
Study Section
Project Start
1990-05-01
Project End
1995-05-31
Budget Start
1992-06-10
Budget End
1992-11-30
Support Year
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
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