Agency
National Institute of Health (NIH)
Institute
Division of Cancer Treatment (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CM057735-002
Application #
3613297
Study Section
Project Start
1985-06-08
Project End
1990-04-30
Budget Start
1986-02-07
Budget End
1986-11-30
Support Year
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Rago, R P; Miles, J M; Sufit, R L et al. (1994) Suramin-induced weakness from hypophosphatemia and mitochondrial myopathy. Association of suramin with mitochondrial toxicity in humans. Cancer 73:1954-9
Bailey, H; Wilding, G; Tutsch, K D et al. (1992) A phase I trial of 5-fluorouracil, leucovorin, and dipyridamole given by concurrent 120-h continuous infusions. Cancer Chemother Pharmacol 30:297-302
Trump, D L; Egorin, M J; Forrest, A et al. (1991) Pharmacokinetic and pharmacodynamic analysis of fluorouracil during 72-hour continuous infusion with and without dipyridamole. J Clin Oncol 9:2027-35
Schiller, J H; Storer, B E; Witt, P L et al. (1991) Biological and clinical effects of intravenous tumor necrosis factor-alpha administered three times weekly. Cancer Res 51:1651-8
Bailey, H; Mulcahy, R T; Tutsch, K D et al. (1991) A phase I study of SR-2508 and cyclophosphamide administered by intravenous injection. Cancer Res 51:1099-104
Bailey, H; Tutsch, K D; Arzoomanian, R Z et al. (1991) Phase I clinical trial of fazarabine as a twenty-four-hour continuous infusion. Cancer Res 51:1105-8
Remick, S C; Grem, J L; Fischer, P H et al. (1990) Phase I trial of 5-fluorouracil and dipyridamole administered by seventy-two-hour concurrent continuous infusion. Cancer Res 50:2667-72
Mulcahy, R T; Trump, D L (1988) Clinical chemosensitization by misonidazole and related compounds: a critical evaluation. J Clin Oncol 6:569-73
Trump, D L; Tutsch, K D; Willson, J K et al. (1987) Phase I clinical trial and pharmacokinetic evaluation of acodazole (NSC 305884), an imidazoquinoline derivative with electrophysiological effects on the heart. Cancer Res 47:3895-900
Trump, D L; Grem, J L; Tutsch, K D et al. (1987) Platinum analogue combination chemotherapy: cisplatin and carboplatin--a phase I trial with pharmacokinetic assessment of the effect of cisplatin administration on carboplatin excretion. J Clin Oncol 5:1281-9

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