Abstract

The objectives of this contract are to provide support services for the Environmental Epidemiology Branch (EEB), Epidemiology and Biostatistics Program (EBP), Division of Cancer Etiology (DCE), National Cancer Institute (NCI) by conducting epidemiologic and natural history studies of hemophiliacs (and persons with related disorders) and their sexual partners and family members; by the maintenance, acquisition and use of epidemiologic data bases; by providing support for collecting and handling biologic specimens and laboratory data; and by statistical analysis of the data.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Epidemiology And Genetics (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CP085649-003
Application #
3634305
Study Section
Project Start
1988-03-25
Project End
1993-03-24
Budget Start
1989-03-14
Budget End
1990-03-24
Support Year
Fiscal Year
1989
Total Cost
Indirect Cost

  Institution

Name
Research Triangle Institute
Department
Type
DUNS #
131606022
City
Research Triangle Park
State
NC
Country
United States
Zip Code
27709

  Publications

Michael, N L; Nelson, J A; KewalRamani, V N et al. (1998) Exclusive and persistent use of the entry coreceptor CXCR4 by human immunodeficiency virus type 1 from a subject homozygous for CCR5 delta32. J Virol 72:6040-7
O'Brien, T R; Blattner, W A; Waters, D et al. (1996) Serum HIV-1 RNA levels and time to development of AIDS in the Multicenter Hemophilia Cohort Study. JAMA 276:105-10
Goedert, J J; Garvey, L; Hilgartner, M W et al. (1994) Risk of HIV infection and AIDS in women and girls with coagulation disorders. AIDS 8:564-5
Kroner, B L; Rosenberg, P S; Aledort, L M et al. (1994) HIV-1 infection incidence among persons with hemophilia in the United States and western Europe, 1978-1990. Multicenter Hemophilia Cohort Study. J Acquir Immune Defic Syndr 7:279-86
Eyster, M E; Fried, M W; Di Bisceglie, A M et al. (1994) Increasing hepatitis C virus RNA levels in hemophiliacs: relationship to human immunodeficiency virus infection and liver disease. Multicenter Hemophilia Cohort Study. Blood 84:1020-3
Eyster, M E; Rabkin, C S; Hilgartner, M W et al. (1993) Human immunodeficiency virus-related conditions in children and adults with hemophilia: rates, relationship to CD4 counts, and predictive value. Blood 81:828-34
Eyster, M E; Diamondstone, L S; Lien, J M et al. (1993) Natural history of hepatitis C virus infection in multitransfused hemophiliacs: effect of coinfection with human immunodeficiency virus. The Multicenter Hemophilia Cohort Study. J Acquir Immune Defic Syndr 6:602-10
Rabkin, C S; Hilgartner, M W; Hedberg, K W et al. (1992) Incidence of lymphomas and other cancers in HIV-infected and HIV-uninfected patients with hemophilia. JAMA 267:1090-4
Eyster, M E; Alter, H J; Aledort, L M et al. (1991) Heterosexual co-transmission of hepatitis C virus (HCV) and human immunodeficiency virus (HIV). Ann Intern Med 115:764-8
Eyster, M E; Ballard, J O; Gail, M H et al. (1989) Predictive markers for the acquired immunodeficiency syndrome (AIDS) in hemophiliacs: persistence of p24 antigen and low T4 cell count. Ann Intern Med 110:963-9

Showing the most recent 10 out of 11 publications