The purpose of this project is to develop a safe, relatively inexpensive, accurate and non-invasive technique for the prenatal diagnosis of genetic disorders by isolating fetal cells in maternal peripheral blood during the first trimester of pregnancy. Cyto- trophoblast-specific antibodies will be produced and will be used to isolate the fetal cells with the aid of a fluorescence-activated cell sorter. The isolated fetal cells can then be used for the prenatal diagnosis of cytogenetic, biochemical or DNA abnormalities.

Project Start
1987-12-31
Project End
1991-12-31
Budget Start
1991-04-02
Budget End
1991-12-31
Support Year
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Dentistry
Type
Schools of Dentistry
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143