The objective of this contract is to perform research leading to the development of a miniature tether-free electromechanically actuated implantable cardiac replacement system. An implantable cardiac replacement system as defined here includes biventricular support which assist the right and left ventricles which remain in situ and the total artificial heart which replaces the excised natural heart. The implantable subsystems of the replacement system include right and left heart blood pumps, and electromechanical energy converter(s), appropriate control systems, and implantable battery pack to provide short-term energy source for the system, a variable volume device and a mechanism for delivering electrical energy for outside to inside the body. The external battery pack will include electrochemical batteries, charging circuitry, and system monitor/diagnostic circuitry.

Agency
National Institute of Health (NIH)
Institute
Division of Heart And Vascular Diseases (NHLBI)
Type
Research and Development Contracts (N01)
Project #
N01HV088105-004
Application #
3662271
Study Section
Project Start
1988-01-01
Project End
1993-09-30
Budget Start
1990-12-20
Budget End
1992-09-30
Support Year
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Pennsylvania State University
Department
Type
Schools of Medicine
DUNS #
129348186
City
Hershey
State
PA
Country
United States
Zip Code
17033
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Baldwin, J T; Deutsch, S; Geselowitz, D B et al. (1990) Estimation of Reynolds stresses within the Penn State left ventricular assist device. ASAIO Trans 36:M274-8
Baldwin, J T; Tarbell, J M; Deutsch, S et al. (1989) Mean flow velocity patterns within a ventricular assist device. ASAIO Trans 35:429-33