The Contractor shall undertake performance of a clinical trial to evaluate the safety and efficacy of an investigational antiepileptic drug (ADD 94057) in a minimum of 8 patients with therapy-resistant partial seizures. This contract is one of two centers that will participate in this trial. A total of 16 patients shall be studied. Patients shall undergo a single dose pharmacokinetic study, a 32-day baseline period, followed by six, 5-week, double-blind treatment periods.

Project Start
1991-04-15
Project End
1993-02-09
Budget Start
1992-06-25
Budget End
1993-02-09
Support Year
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Neurology
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Privitera, M D; Treiman, D M; Pledger, G W et al. (1994) Dezinamide for partial seizures: results of an n-of-1 design trial. Neurology 44:1453-8