Parasitic diseases continue to be an important cause of morbidity and mortality worldwide. The last decade has provided a series of new tools for parasite control, however these are not yet thoroughly applied in developing countries where most emerging and re-emerging parasitic infections occur. This program aims to strengthen and interrelate three already existing research lines in Peru, that will be used as a comprehensive framework for the concerted use of these new tools. A core structure covering immunology/parasitology and epidemiology/GIS/data management will enhance the shared use of new technology for the diagnosis, treatment, and control of endemic parasitic diseases. In order to improve E. granulosus control methods, fast-track alternatives will be sought in Project 1 by defining transmission dynamics, targeting the definitive host. In Project 2, new synthetic peptides will be screened and used in a field applicable format to detect individuals with brain T. solium cysticercosis before the appearance of symptoms to determine the utility of pre-symptomatic antiparasitic therapy, and in Project 3, the basic patterns of transmission in endemic zones of Cyclospora cayetanensis, a new human pathogen protozoa described and named at the Universidad Peruana Cayetano Heredia, the applicant institution, will be defined.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
5P01AI051976-02
Application #
6663221
Study Section
Special Emphasis Panel (ZAI1-GLM-M (J2))
Program Officer
Rao, Malla R
Project Start
2002-09-30
Project End
2007-06-30
Budget Start
2003-07-01
Budget End
2004-06-30
Support Year
2
Fiscal Year
2003
Total Cost
$667,596
Indirect Cost
Name
Universidad Peruana Cayetano Heredia
Department
Type
DUNS #
934798430
City
Lima
State
Country
Peru
Zip Code
LIMA -31
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