This interdisciplinary program of research is designed to investigate seven major issues. They relate to Eustachian tube function, otitis media in infants, variation in pressures exerted by the velopharyngeal valving mechanism, the effects on speech of oronasal fistulae, the anatomy of the pharynx, and pattern recognition of nasal capsular anatomy. Methods include animal, cadaver, human, and instrumental approaches.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Program Projects (P01)
Project #
5P01DE001697-23
Application #
3094906
Study Section
(SSS)
Project Start
1977-12-01
Project End
1986-03-31
Budget Start
1985-03-01
Budget End
1986-03-31
Support Year
23
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
Schools of Dentistry/Oral Hygn
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Edington, H D; Mooney, M P; Losken, A et al. (1998) The effects of soft-tissue expansion on lip repair and midfacial growth in a rabbit cleft lip model. Ann Plast Surg 41:171-9
Smith, T D; Siegel, M I; Mooney, M P et al. (1997) Formation and enlargement of the paranasal sinuses in normal and cleft lip and palate human fetuses. Cleft Palate Craniofac J 34:483-9
Smith, T D; Siegel, M I; Mooney, M P et al. (1997) Prenatal growth of the human vomeronasal organ. Anat Rec 248:447-55
Vergato, L A; Doerfler, R J; Mooney, M P et al. (1997) Mouse palatal width growth rates as an ""at risk"" factor in the development of cleft palate induced by hypervitaminosis A. J Craniofac Genet Dev Biol 17:204-10
Anemone, R L; Mooney, M P; Siegel, M I (1996) Longitudinal study of dental development in chimpanzees of known chronological age: implications for understanding the age at death of Plio-Pleistocene hominids. Am J Phys Anthropol 99:119-33
Smith, T D; Siegel, M I; Mooney, M P et al. (1996) Vomeronasal organ growth and development in normal and cleft lip and palate human fetuses. Cleft Palate Craniofac J 33:385-94
Elliott, M A; Studen-Pavlovich, D A; Ranalli, D N (1995) Prevalence of selected pediatric conditions in children with Pierre Robin sequence. Pediatr Dent 17:106-11
Mooney, M P; Siegel, M I; Kimes, K R et al. (1994) Anterior paraseptal cartilage development in normal and cleft lip and palate human fetal specimens. Cleft Palate Craniofac J 31:239-45
Losken, A; Mooney, M P; Siegel, M I (1994) Comparative cephalometric study of nasal cavity growth patterns in seven animal models. Cleft Palate Craniofac J 31:17-23
Paradise, J L; Elster, B A; Tan, L (1994) Evidence in infants with cleft palate that breast milk protects against otitis media. Pediatrics 94:853-60

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