category and author. The OO will be responsible for assuring Center credit when appropriate by includes tracking of all publications and presentations that use Core facilities. Scientific Steering Committee (SSC). The SSC is an internal advisory committee, which will consist of the JHU NIMH CENTER director and co-directors, the Core directors and eight members representing the disciplines of education, therapeutics, epidemiology, international research and pathogenesis. These are somewhat arbitrary classifications intended to have substantial overlap while covering a broad spectrum of Proteomics, HIV and drug abuse research interests at this institution.
Protein biomarkers can provide accurate diagnoses, help prevent or monitor therapies in disease. Mass spectrometry provides one of the major analytical methods for proteomics, including biomarker discovery and validation. Because protein expression in CSF spans several orders of magnitude, chromatography and bioinformatics tools are essential parts of this approach, which will be applied to all of the proposed projects.
|Saylor, Deanna; Dickens, Alex M; Sacktor, Ned et al. (2016) HIV-associated neurocognitive disorder--pathogenesis and prospects for treatment. Nat Rev Neurol 12:234-48|
|Tharakan, Ravi; Edwards, Nathan; Graham, David R M (2010) Data maximization by multipass analysis of protein mass spectra. Proteomics 10:1160-71|